Fundamentals of Toxicologic Pathology

Front Cover
Matthew A. Wallig, Wanda M Haschek, Colin G. Rousseaux
Academic Press, Nov 23, 2009 - Medical - 714 pages

Toxicologic pathology integrates toxicology and the disciplines within it (such as biochemistry, pharmacodynamics and risk assessment) to pathology and its related disciplines (such as physiology, microbiology, immunology, and molecular biology).

Fundamentals of Toxicologic Pathology Second Edition updates the information presented in the first edition, including five entirely new chapters addressing basic concepts in toxicologic pathology, along with color photomicrographs that show examples of specific toxicant-induced diseases in animals. The current edition also includes comparative information that will prove a valuable resource to practitioners, including diagnostic pathologists and toxicologists.

  • 25% brand new information, fully revised throughout
  • New chapters: Veterinary Diagnostic Toxicologic Pathology; Clinical Pathology; Nomenclature: Terminology for Morphologic Alterations; Techniques in Toxicologic Pathology
  • New color photomicrographs detailing specific toxicant-induced diseases in animals
  • Mechanistic information integrated from both toxicology and pathology discussing basic mechanisms of toxic injury and morphologic expression at the subcellular, cellular, and tissue levels
 

Contents

CHAPTER 1 PRINCIPLES OF TOXICOLOGY
1
CELL INJURYDEATH AND CHEMICAL CARCINOGENESIS
9
CHAPTER 3 CLINICAL PATHOLOGY
43
TERMINOLOGY FOR MORPHOLOGIC ALTERATIONS
67
CHAPTER 5 TECHNIQUES IN TOXICOLOGIC PATHOLOGY
81
CHAPTER 6 RESPIRATORY SYSTEM
93
CHAPTER 7 SKIN AND ORAL MUCOSA
135
CHAPTER 8 GASTROINTESTINAL TRACT
163
CHAPTER 12 CARDIOVASCULAR AND SKELETAL MUSCLE SYSTEMS
319
CHAPTER 13 NERVOUS SYSTEM
377
CHAPTER 14 BONES AND JOINTS
411
CHAPTER 15 IMMUNE SYSTEM
451
CHAPTER 16 HEMATOPOIETIC SYSTEM
491
CHAPTER 17 ENDOCRINE SYSTEM
513
CHAPTER 18 MALE REPRODUCTIVE SYSTEM
553
CHAPTER 19 FEMALE REPRODUCTIVE SYSTEM
599

CHAPTER 9 THE LIVER
197
CHAPTER 10 PANCREAS
237
CHAPTER 11 KIDNEY AND LOWER URINARY TRACT
261
CHAPTER 20 DEVELOPMENTAL PATHOLOGY
633
Index
673
Copyright

Other editions - View all

Common terms and phrases

About the author (2009)

Matthew A. Wallig, DVM, Ph.D., DACVP, is Professor Emeritus in the Department of Pathobiology, College of Veterinary Medicine, the Department of Food Science and Human Nutrition, as well as the Division of Nutritional Sciences at the University of Illinois. His research has focused on the chemoprotective properties and mechanisms of phytochemicals in the diet, in particular those in cruciferous vegetables, soy, and tomatoes. His current interests have expanded to include defining morphologic parameters for diagnostic quantitative ultrasound in pancreatitis, pancreatic and hepatic neoplasia, metastatic disease, and chronic hepatic diseases such as nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Matt has served as an Editor for the last two editions of the Fundamentals of Toxicologic Pathology and Haschek and Rousseaux’s Handbook of Toxicologic Pathology.

Professor Haschek-Hock has served as president of the Society of Toxicologic Pathology and the Society of Toxicology’s Comparative and Veterinary Specialty Section, as well as Councilor of the American College of Veterinary Pathologists, board member of the American Board of Toxicology; as Associate Editor for Toxicological Sciences and for Toxicologic Pathology; as Editorial Board member for Fundamental and Applied Toxicology, Veterinary Pathology and Toxicologic Pathology. She has served as a member on the USFDA Veterinary Medicine Advisory Committee for the Center for Veterinary Medicine, the EPA’s FIFRA Science Advisory Panel, and National Academy of Sciences Committee. She currently serves on the Board of Directors of the C.L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology. She was awarded the Society of Toxicologic Pathology’s Achievement Award in 2007 and the Midwest Regional Chapter – Society of Toxicology’s Kenneth DuBois Award in 2011.

Colin G. Rousseaux, BVSc, Ph.D., DABT, FIATP, is also a Fellow of the Royal College of Pathology (FRCPath) and Fellow of the Academy of Toxicological Sciences (FATS). He is a Professor (Adjunct) in the Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of Ottawa, Canada. He has over 35 years of experience in comparative and toxicologic pathology with a research focus on herbal remedies, fetal development and teratology, and environmental pollutants. He has described, investigated, and evaluated numerous toxicologic pathology issues associated with pharmaceuticals, pesticides, and agrochemicals. He has served on the editorial board of Toxicologic Pathology. He is a former President of the STP. Colin served as an Editor for the three editions of the Fundamentals of Toxicologic Pathology and Haschek and Rousseaux’s Handbook of Toxicologic Pathology.

Bibliographic information