2996-42500

TREASURY DEPARTMENT

Public Health and Marine-Hospital Service of the United States

HYGIENIC LABORATORY. BULLETIN No. 48

DECEMBER, 1908

THE PHYSIOLOGICAL STANDARD-
IZATION OF DIGITALIS

:

By

CHARLES WALLIS EDMUNDS

and

WORTH HALE

WASHINGTON

GOVERNMENT PRINTING OFFICE

C

CONTENTS.

Page.

1. Introduction.....

7

2. Chemistry of digitalis....

3. Relationship of digitoxin content to physiological activity.

4. Variability of digitalis preparations...

5. Literature relating to standardization methods.

6. Summary of standardization literature...

7

8

10

16

31