Handbook of Biologically Active PeptidesAbba Kastin, Abba J. Kastin Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity. |
From inside the book
Results 1-5 of 82
Page 2
... similar in sequence to 4k-P may be present in carrot, rice, or Arabidopsis. Immunocytochemistry has shown that 4k-P is localized around the plasma membranes and cell walls. The subcellular localization of 4k-P is similar to that of 43k ...
... similar in sequence to 4k-P may be present in carrot, rice, or Arabidopsis. Immunocytochemistry has shown that 4k-P is localized around the plasma membranes and cell walls. The subcellular localization of 4k-P is similar to that of 43k ...
Page 12
... similar to the CLV3 genomic structure [6, 14]. AtCLEs encode peptides and polypeptides of 80–120 residues. They share several common structural features including an amino terminal signal peptide or membrane anchor and a conserved 14 ...
... similar to the CLV3 genomic structure [6, 14]. AtCLEs encode peptides and polypeptides of 80–120 residues. They share several common structural features including an amino terminal signal peptide or membrane anchor and a conserved 14 ...
Page 13
... similar to clv3 null alleles, recent work has shown that these strong clv1 alleles are dominant-negative and that clv1 null alleles exhibit weak phenotypes [8]. Thus, CLV3 still has a role in limiting stem cells in a clv1-null mutant ...
... similar to clv3 null alleles, recent work has shown that these strong clv1 alleles are dominant-negative and that clv1 null alleles exhibit weak phenotypes [8]. Thus, CLV3 still has a role in limiting stem cells in a clv1-null mutant ...
Page 20
... similar phenotypes as overexpression of ROT4 alone. Based on their findings, we then tried to test if overexpression of other DVL family members fused with GFP would show the similar phenotypes as the DVL members alone did. The results ...
... similar phenotypes as overexpression of ROT4 alone. Based on their findings, we then tried to test if overexpression of other DVL family members fused with GFP would show the similar phenotypes as the DVL members alone did. The results ...
Page 38
... similar to the rot4-1D mutant when it is overexpressed [8], suggesting that RTFL proteins share similar functions in Arabidopsis. RTFL genes are also found in other seed plants, such as Oryza sativa (rice), Glycine max (soybean), and ...
... similar to the rot4-1D mutant when it is overexpressed [8], suggesting that RTFL proteins share similar functions in Arabidopsis. RTFL genes are also found in other seed plants, such as Oryza sativa (rice), Glycine max (soybean), and ...
Contents
1 | |
55 | |
125 | |
157 | |
261 | |
Venom Peptides Section | 339 |
CancerAnticancer Peptides Section | 421 |
Vaccine Peptides Section | 491 |
Gastrointestinal Peptides Section | 999 |
Cardiovascular Peptides Section | 1163 |
Renal Peptides Section | 1227 |
Respiratory Peptides Section | 1283 |
Opioid Peptides Section | 1313 |
Neurotrophic Peptides Section | 1379 |
BloodBrain Barrier Peptides Section | 1415 |
Other Peptide Topics | 1481 |
Immunological and Inflammatory Peptides Section | 547 |
Brain Peptides Section | 621 |
Endocrine Peptides Section | 829 |
Ingestive Peptides Section | 889 |
Index | 1565 |
Color Plates | 1597 |
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Common terms and phrases
Acad action activity addition amino acids amphibian analogs analysis antagonists antibodies antigen antimicrobial binding Biochem Biol Biologically Active brain breast C-terminal cancer cause cDNA cells channels characterized Chem cloned common complex conserved contain demonstrated derived determined disease disulfide domain effects encoding epitopes expression factor frog function gene growth hormone human identified immune important increase indicate induced inhibition insect interaction involved isolated known levels ligands lines major mechanism mediated membrane mice molecular molecules mRNA multiple muscle Nature neurons neuropeptide novel observed organs patients peptide plants position potential precursor present processing produced protein recently receptor region regulation release residues response role secretion selective sequence showed shown signal similar skin specific stimulate structure studies suggesting surface synthetic Table tion tissues toxins treatment tumor University vaccine various venom
Popular passages
Page 403 - WITCH. Fillet of a fenny snake, In the cauldron boil and bake; Eye of newt and toe of frog, Wool of bat and tongue of dog, Adder's fork and blind-worm's...
Page 565 - Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S., Kitamura, Y, Yoshida, N., Kikutani, H., and Kishimoto, T. (1996). Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1.
Page 600 - Houghten, RA (1985) General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.
Page 505 - D. (1998) Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. 4, 328-332 (see comments).
Page 594 - AJ (1986) The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides.
Page 498 - Slamon DJ, Leyland-jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
Page 564 - Feng, Y., Broder, CC, Kennedy, PE, and Berger, EA (1996) HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor.
Page 564 - The lymphocyte chemoattractant SDF-1- is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382: 829-833.
Page 601 - DW (1997). A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis.
Page 504 - Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of human histocompatibility leukocyte antigen (HLA)-A2binding peptide epitopes. J. Exp. Med..