Handbook of Biologically Active PeptidesAbba Kastin, Abba J. Kastin Peptides play a crucial role in many physiological processes including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The Handbook of Biologically Active Peptides presents, for the first time, this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. The Handbook of Biologically Active Peptides is a definitive, all-encompassing reference that will be indispensable for individuals ranging from peptide researchers, to biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and to endocrinologists. Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas with which they would not ordinarily be familiar. *Chapters are designed to be a source for workers in the field and will enable researchers working in a specific area to examine other related areas that they would not ordinarily be familiar.*Fascinating relationships described in the book include the presence of some peptides originally found in frog skin that persist in the human human and brain where they can affect food intake and obesity. |
From inside the book
Results 1-5 of 78
Page xl
... common to several chapters dealing with mammalian peptides would be discussed primarily in the Brain Peptides Section. For other sections, such as GI Peptides, this same outline is followed except that the focus is specific for the GI ...
... common to several chapters dealing with mammalian peptides would be discussed primarily in the Brain Peptides Section. For other sections, such as GI Peptides, this same outline is followed except that the focus is specific for the GI ...
Page 12
... common structural features including an amino terminal signal peptide or membrane anchor and a conserved 14 amino acid carboxyl terminal domain that defines the signature of this gene family, termed the CLE domain (Fig. 3C) [6, 7]. This ...
... common structural features including an amino terminal signal peptide or membrane anchor and a conserved 14 amino acid carboxyl terminal domain that defines the signature of this gene family, termed the CLE domain (Fig. 3C) [6, 7]. This ...
Page 13
... common pathway [5, 37]. clv3 null mutants have the most severe phenotypes and are epistatic at the meristem to mutations in clv1 and clv2 [15, 37]. Based on the genetic interactions and the protein structures, CLV3 was proposed to be a ...
... common pathway [5, 37]. clv3 null mutants have the most severe phenotypes and are epistatic at the meristem to mutations in clv1 and clv2 [15, 37]. Based on the genetic interactions and the protein structures, CLV3 was proposed to be a ...
Page 51
... common ancestral precursor. A comparison of the nucleotide and amino acid sequences of LeproHypSys with those of NtproHypSys indicate that they have evolved from a common ancestral protein [19, 20]. A 10-amino-acid sequence is present ...
... common ancestral precursor. A comparison of the nucleotide and amino acid sequences of LeproHypSys with those of NtproHypSys indicate that they have evolved from a common ancestral protein [19, 20]. A 10-amino-acid sequence is present ...
Page 58
... common feature of defensins in both animals and plants is that they can in many cases be induced by pathogen-associated molecular patterns (PAMPs) [6, 15, 24]. The regulatory mechanisms show a remarkable analogy, although it is ...
... common feature of defensins in both animals and plants is that they can in many cases be induced by pathogen-associated molecular patterns (PAMPs) [6, 15, 24]. The regulatory mechanisms show a remarkable analogy, although it is ...
Contents
1 | |
55 | |
125 | |
157 | |
261 | |
Venom Peptides Section | 339 |
CancerAnticancer Peptides Section | 421 |
Vaccine Peptides Section | 491 |
Gastrointestinal Peptides Section | 999 |
Cardiovascular Peptides Section | 1163 |
Renal Peptides Section | 1227 |
Respiratory Peptides Section | 1283 |
Opioid Peptides Section | 1313 |
Neurotrophic Peptides Section | 1379 |
BloodBrain Barrier Peptides Section | 1415 |
Other Peptide Topics | 1481 |
Immunological and Inflammatory Peptides Section | 547 |
Brain Peptides Section | 621 |
Endocrine Peptides Section | 829 |
Ingestive Peptides Section | 889 |
Index | 1565 |
Color Plates | 1597 |
Other editions - View all
Common terms and phrases
Acad action activity addition amino acids amphibian analogs analysis antagonists antibodies antigen antimicrobial binding Biochem Biol Biologically Active brain breast C-terminal cancer cause cDNA cells channels characterized Chem cloned common complex conserved contain demonstrated derived determined disease disulfide domain effects encoding epitopes expression factor frog function gene growth hormone human identified immune important increase indicate induced inhibition insect interaction involved isolated known levels ligands lines major mechanism mediated membrane mice molecular molecules mRNA multiple muscle Nature neurons neuropeptide novel observed organs patients peptide plants position potential precursor present processing produced protein recently receptor region regulation release residues response role secretion selective sequence showed shown signal similar skin specific stimulate structure studies suggesting surface synthetic Table tion tissues toxins treatment tumor University vaccine various venom
Popular passages
Page 403 - WITCH. Fillet of a fenny snake, In the cauldron boil and bake; Eye of newt and toe of frog, Wool of bat and tongue of dog, Adder's fork and blind-worm's...
Page 565 - Nagasawa, T., Hirota, S., Tachibana, K., Takakura, N., Nishikawa, S., Kitamura, Y, Yoshida, N., Kikutani, H., and Kishimoto, T. (1996). Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1.
Page 600 - Houghten, RA (1985) General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.
Page 505 - D. (1998) Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells. Nat. Med. 4, 328-332 (see comments).
Page 594 - AJ (1986) The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides.
Page 498 - Slamon DJ, Leyland-jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
Page 564 - Feng, Y., Broder, CC, Kennedy, PE, and Berger, EA (1996) HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor.
Page 564 - The lymphocyte chemoattractant SDF-1- is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 1996;382: 829-833.
Page 601 - DW (1997). A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis.
Page 504 - Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of human histocompatibility leukocyte antigen (HLA)-A2binding peptide epitopes. J. Exp. Med..