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ploy in each case a medicine which possesses the quality to generate a similar affection in the healthy system.

In illustration of my principle, I would but select a few remedies, (many of which are in daily use) whose invariable effect, in many striking cases, does not depend on any particularity, but acts only in accordance to the similarity, homeopathically.

Mercury, in large doses, produces ulcers in the throat, similar to those of the syphilitic, in consequence of which. it affects this disease specifically,

Atropa belladonna, deadly nightshade, causes morbid symptoms similar to hydrophobia, in which disease that remedy proves to be very beneficial. Dryness of the throat and difficulty in swallowing are the most prominent symptoms occasened by this remedy, which are also characteristic in hydrophobia.

The dryness of the throat is not a constant symptom. It is often, however, very distinct. It occurred, for example, in 150 soldiers, who were poisoned near Dresden, as related by M. Gauttier de Claubry;* and in six soldiers, whose cases have been described by Mr. Brumwell. The former had not only dryness of that throat, but likewise difficulty in swallowing..

*Sedillot's Journal de Med., Dec. 1813, 364. †London Med. Obs. and Inquirer, vi. 523

lungs and air passages-almost always shortness of breath.

In many instances too, the urinary passages are affected, the patient being harassed with frequent painful and difficult micturition, sometimes total suppression of urine.

When the symptoms of irritation of the alimentary canal have subsisted a few hours, convulsive motions often occur in a greater or less degree. They are seldom violent, and generally consist of nothing else than tremors and twitches. Another affection, and a very distressing one, is cramps of the legs and arms. This symptom may be a concomitant of every kind of diarr hoa; but in that caused by arsenic, it is peculiarly severe and frequent.

The general system always sympathises acutely with the local derangement. The pulse commonly becomes very small, feeble, and rapid, soon after the vomiting sets in; and in no long time it is even imperceptible. This state of the pulse is naturally attended with great coldness, clammy sweats, and even lividity of the feet and hands.

The countenance is commonly collapsed from an early period, and almost always expressive of great torture and extreme anxiety.

Death, in general, comes on calmly, but is sometimes preceded by a paroxysm of convulsions. Various exceptions have at times been observed, resembling petechia or measles, or red miliaria, another external affection which may be noticed, is general swellings of the body.

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The poisonous effects produced by arsenic bears the strongest resemblance to that dreadful malady called Cholera Asiatica, for which striking resemblance, many homoeopathic physicians called the cholera morbus arsenicalis.

The most marked symptoms of the cholera, we are well aware, are purging, vomiting, burning pain in the stomach, incessant desire for water, cramps of arms and legs, coldness of the surface, pulse imperceptible, hoarseness, the skin discolored. Arsenic and veratrum, which latter remedy produces similar symptoms on healthy bodies, as the former were, in minute doses, (the decillion part of a grain) the most effectual means by which the ho moeopathic practitions rescued thousand and thousand lives from that torturing malady.

Aqua Calcis produces an excessive discharge of urine; and the same remedy lessens, also, the too abundant secretion of urine in diabetes.

Helleborus Albus, known already to the ancients as an active remedy in mental aberrations, effects in similar way when taken by healthy individuals.

Datura Stramonium,- Thorn Apple. The symptoms produced by a poisonous dose in man are variable. The leading features are maniacal delirium, convulsions, incessant unconnected talk like that of demency. Its heal

Rheubarb, which is a purgative, given in a large dose, checks looseness of the bowels in a very small quantity.

Opium, which possesses the peculiar quality to stop diarrhœa, is, according to Wirthensohn, Bell, Heister, a most excellent remedy in obstructions, in consequence of ileus and hernia incarcerata.

Opium, administered in very small quantities, acts like a charm in nervous fevers, accompanied with a state called coma somnolontum, a kind of sleep with short remissions, or intervals of imperfect waking, sensation, and sleep.

A strong infusion of tea effects some persons very strongly, and causes palpitation of the heart, anxiety, which is often a very good remedy to relieve those distressing symptoms.

Pulsatilla pratensis nigricans,—the wind flower.This remedy, tried on healthy persons, effects dimness of sight, and proves to be very beneficial in some species of amaurosis.

Copper-Ammonium, which produces violent spasms, ac cording to the observation of Pfaendel and Burdach, was

already used by Aretaeus successfully in epilepsia. Modern physicians have made the experiment, and concur in opinion that it subdues spasmodic affections.

Hyoscyamus,- Blachenbane. The effects of this remedy on men is very poisonous :- marked symptoms are agitations, convulsions, risus sardonius, extravagant delirium, etc. Homeopathic physicians have used it with success in nervous fevers, in which there was that singular union of delirium and coma termed usually typhomania.

Arsenic. Soon after the remedy is taken, sickness begins, or about the same time the region of the stomach feels painful. The pain being commonly of a burning kind, (very characteristic) violent fits of vomiting and retching then speedily ensue, especially when drink is taken. There is often, also, a sense of dryness, heat, and tightness in the throat, creating an incessant desire for drink; and this affection of the throat often precedes the vomiting. Occasionally it is altogether wanting, at other times it is so severe as to be attended with fits of suffocation and convulsive vomiting at the sight of fluids. Hoarsoness and difficulty of speech (voz cholerica) are commonly combined with it.

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In no long time after the first illness, diarrœha generally makes its appearance. The patient is often tormented by frequent and ineffectual calls.

There are likewise present signs of irritation of the

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