Robbins Pathologic Basis of DiseasePresenting the latest edition of this popular, comprehensive and practical text of pathology. Written with great clarity for easy readability, this reference offers detailed discussions of genetic disorders, cellular injury and death, neoplasia, the skeletal system and soft tissue tumors, and much more. Completely revised and updated, this edition is even more user-friendly with the use of text boxes for key topics in each chapter and a new full-color design. Features 1200 excellent 4-color illustrations! |
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Page 178
... Normal Normal Fragile X pedigree . Note that in the first generation all sons are normal and all females are carriers . During oogenesis in the carrier female , premutation expands to full mutation ; hence in the next generation , all ...
... Normal Normal Fragile X pedigree . Note that in the first generation all sons are normal and all females are carriers . During oogenesis in the carrier female , premutation expands to full mutation ; hence in the next generation , all ...
Page 183
... Normal 000 Direct gene diagnosis : detection of coagulation factor V mutation by polymerase chain reaction ( PCR ) ... ( normal ) oligonucleotide probe MɅMANNNN Normal gene Z. NORMAL 5 ' H 67 bp Mnl 1 sites 163 bp Mnl 1 site PCR primer ...
... Normal 000 Direct gene diagnosis : detection of coagulation factor V mutation by polymerase chain reaction ( PCR ) ... ( normal ) oligonucleotide probe MɅMANNNN Normal gene Z. NORMAL 5 ' H 67 bp Mnl 1 sites 163 bp Mnl 1 site PCR primer ...
Page 184
... ( normal ) oligonucleotide probe MɅMANNNN Normal gene Z oligonucleotide probe Normal allele Mutant allele PCR primers PKD gene Schematic diagram. A. B. HYBRIDIZATION ACCATCGACGACAAAGGGA Strong АССАТC GACААСАА A G G G A Primers Normal MM ...
... ( normal ) oligonucleotide probe MɅMANNNN Normal gene Z oligonucleotide probe Normal allele Mutant allele PCR primers PKD gene Schematic diagram. A. B. HYBRIDIZATION ACCATCGACGACAAAGGGA Strong АССАТC GACААСАА A G G G A Primers Normal MM ...
Contents
Cell Injury and Diseases of Immunity 188 | 1 |
29 | 14 |
Neoplasia 260 | 21 |
Copyright | |
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abnormal acid activation acute adhesion allele amyloidosis angiogenesis antibodies antigens apoptosis associated autosomal bacterial binding cancer carcinoma cause CD4+ cell cycle cell death cell injury cellular Chapter chemokines chromosome chronic clinical coagulation collagen common complex cyclin cytokines damage defects deficiency develop disease disorders edema effects endothelial cells endothelium enzyme epithelial example extracellular extracellular matrix fibrin fibroblasts fibrosis Figure function gene genetic glycogen granules growth factors hepatic host human immune increased induced infarction infection inflammation inflammatory inhibit integrins involved kinase lesions leukocyte lipid liver lung lymphocytes lysosomal macrophages matrix mechanisms mediators membrane metabolism molecular molecules monocytes muscle mutations necrosis neoplasms neutrophils normal occur organs oxidative pathogenesis pathway patients phagocytosis plasma platelet produce proliferation protein pulmonary reactions receptor regulation release renal response result signals skin specific surface syndrome synthesis T-cell thrombi thrombosis tion toxic tumor tumor cells vascular viral virus viruses vitamin