Robbins Pathologic Basis of DiseasePresenting the latest edition of this popular, comprehensive and practical text of pathology. Written with great clarity for easy readability, this reference offers detailed discussions of genetic disorders, cellular injury and death, neoplasia, the skeletal system and soft tissue tumors, and much more. Completely revised and updated, this edition is even more user-friendly with the use of text boxes for key topics in each chapter and a new full-color design. Features 1200 excellent 4-color illustrations! |
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Page 140
... gene , to clone it , and ultimately to determine the molecular changes that affect the gene in patients with the disorder . Because in many common single - gene disorders , such as cystic fibrosis , there was no clue to the nature of ...
... gene , to clone it , and ultimately to determine the molecular changes that affect the gene in patients with the disorder . Because in many common single - gene disorders , such as cystic fibrosis , there was no clue to the nature of ...
Page 285
... gene has been mapped , as well as one of the three immunoglobulin gene - carrying chromosomes . At its normal locus , the expression of the myc gene is tightly controlled and is expressed only during certain stages of the cell cycle ...
... gene has been mapped , as well as one of the three immunoglobulin gene - carrying chromosomes . At its normal locus , the expression of the myc gene is tightly controlled and is expressed only during certain stages of the cell cycle ...
Page 292
... gene . If the p53 gene is mutated , however , the hypoxic tumor cells are resistant to apoptosis . Thus , hypoxia selects for cells in which the p53 gene is inactive , and propagation of p53- deficient cells is favored . In addition to ...
... gene . If the p53 gene is mutated , however , the hypoxic tumor cells are resistant to apoptosis . Thus , hypoxia selects for cells in which the p53 gene is inactive , and propagation of p53- deficient cells is favored . In addition to ...
Contents
Cell Injury and Diseases of Immunity 188 | 1 |
29 | 14 |
Neoplasia 260 | 21 |
Copyright | |
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Common terms and phrases
abnormal acid activation acute adhesion allele amyloidosis angiogenesis antibodies antigens apoptosis associated autosomal bacterial binding cancer carcinoma cause CD4+ cell cycle cell death cell injury cellular Chapter chemokines chromosome chronic clinical coagulation collagen common complex cyclin cytokines damage defects deficiency develop disease disorders edema effects endothelial cells endothelium enzyme epithelial example extracellular extracellular matrix fibrin fibroblasts fibrosis Figure function gene genetic glycogen granules growth factors hepatic host human immune increased induced infarction infection inflammation inflammatory inhibit integrins involved kinase lesions leukocyte lipid liver lung lymphocytes lysosomal macrophages matrix mechanisms mediators membrane metabolism molecular molecules monocytes muscle mutations necrosis neoplasms neutrophils normal occur organs oxidative pathogenesis pathway patients phagocytosis plasma platelet produce proliferation protein pulmonary reactions receptor regulation release renal response result signals skin specific surface syndrome synthesis T-cell thrombi thrombosis tion toxic tumor tumor cells vascular viral virus viruses vitamin