Robbins Pathologic Basis of DiseasePresenting the latest edition of this popular, comprehensive and practical text of pathology. Written with great clarity for easy readability, this reference offers detailed discussions of genetic disorders, cellular injury and death, neoplasia, the skeletal system and soft tissue tumors, and much more. Completely revised and updated, this edition is even more user-friendly with the use of text boxes for key topics in each chapter and a new full-color design. Features 1200 excellent 4-color illustrations! |
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Page 96
... Cyclin E G1 Cyclin A Cyclin B G2 M Go Inactive CDK1 kinase CDK1 cyclin B B cyclin Degraded Active kinase A B Figure 4-7 CDK cyclin Inhibit CDK1 cyclin B Inactive kinase Controls G2 M transition Cyclin - Dependent Kinase Inhibitors p21 ...
... Cyclin E G1 Cyclin A Cyclin B G2 M Go Inactive CDK1 kinase CDK1 cyclin B B cyclin Degraded Active kinase A B Figure 4-7 CDK cyclin Inhibit CDK1 cyclin B Inactive kinase Controls G2 M transition Cyclin - Dependent Kinase Inhibitors p21 ...
Page 283
... cyclins and cyclin - dependent kinases ( CDKS ) in regulating the cell cycle . In the depicted example , inactive CDK is constitutively expressed ; it is activated by binding to cyclin D , which is synthesized in G ,. The activated CDK ...
... cyclins and cyclin - dependent kinases ( CDKS ) in regulating the cell cycle . In the depicted example , inactive CDK is constitutively expressed ; it is activated by binding to cyclin D , which is synthesized in G ,. The activated CDK ...
Page 284
... Cyclin A TTT CDK inhibitors Table 8-9 . SELECTED TUMOR - SUPPRESSOR GENES INVOLVED IN. CDK inhibitors p16 CDK inhibitors P15 P18 P19 IIII G1 p21 p27 p57 III Cyclin E CDK inhibitors p27 CDK2 I p57 Cyclin Cyclin D D CDK4 CDK6 CDK2 pRb pRb ...
... Cyclin A TTT CDK inhibitors Table 8-9 . SELECTED TUMOR - SUPPRESSOR GENES INVOLVED IN. CDK inhibitors p16 CDK inhibitors P15 P18 P19 IIII G1 p21 p27 p57 III Cyclin E CDK inhibitors p27 CDK2 I p57 Cyclin Cyclin D D CDK4 CDK6 CDK2 pRb pRb ...
Contents
Cell Injury and Diseases of Immunity 188 | 1 |
29 | 14 |
Neoplasia 260 | 21 |
Copyright | |
23 other sections not shown
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Common terms and phrases
abnormal acid activation acute adhesion allele amyloidosis angiogenesis antibodies antigens apoptosis associated autosomal bacterial binding cancer carcinoma cause CD4+ cell cycle cell death cell injury cellular Chapter chemokines chromosome chronic clinical coagulation collagen common complex cyclin cytokines damage defects deficiency develop disease disorders edema effects endothelial cells endothelium enzyme epithelial example extracellular extracellular matrix fibrin fibroblasts fibrosis Figure function gene genetic glycogen granules growth factors hepatic host human immune increased induced infarction infection inflammation inflammatory inhibit integrins involved kinase lesions leukocyte lipid liver lung lymphocytes lysosomal macrophages matrix mechanisms mediators membrane metabolism molecular molecules monocytes muscle mutations necrosis neoplasms neutrophils normal occur organs oxidative pathogenesis pathway patients phagocytosis plasma platelet produce proliferation protein pulmonary reactions receptor regulation release renal response result signals skin specific surface syndrome synthesis T-cell thrombi thrombosis tion toxic tumor tumor cells vascular viral virus viruses vitamin