Heterocyclic ChemistryThis book deals with the fundamental chemistry of fully saturated and unsaturated 4-, 5- and 6-membered heterocycles. The principal focus is those compounds containing a single nitrogen, oxygen or sulfur atom and by restricting discussion to these, a balanced treatment is possible. The book introduces a selection of important heterocyclic compounds and the vital role that they play in life, medicine and industry. Conformational aspects of heterocyclic chemistry, aromatic stabilization, nomenclature, reaction mechanisms and methods of synthesis are also discussed. Ideal for the needs of undergraduate chemistry students, Tutorial Chemistry Texts is a major series consisting of short, single topic or modular texts concentrating on the fundamental areas of chemistry taught in undergraduate science courses. Each book provides a concise account of the basic principles underlying a given subject, embodying an independent-learning philosophy and including worked examples. |
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I LOVE THE PAGE ON the exhaustive methylation of an ‘unknown’ piperidine. Great work!
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great information for me thanks alot
Contents
Introduction to Heterocyclic Chemistry | 1 |
Benzopyridines | 29 |
5 | 65 |
6 | 72 |
7 | 89 |
8 | 115 |
Answers to Problems | 125 |
141 | |
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Common terms and phrases
acetic acid addition adduct aldehyde alkyl anion aqueous aromatic atom attack base benzene bond carbon carbonyl cation Chapter charge Chem Chemistry chloride CO₂Et CO₂H CO₂Me compounds conformations conjugate containing corresponding cyclization delocalized deprotonated derivatives double effect electrons electrophiles enamine example favoured followed furan further give H H H H₂O heat Heterocyclic Heterocyclic Chemistry HOAC hydride hydrogen important indole initial intermediate involved isoquinoline ketone known lone pair mechanism method methyl molecule N-oxide names NaOH nature nitrogen atom normally Note nucleophilic obtained occurs OH OH oxidation oxygen atom piperidine planar position possible presence Problem proton provides pyridine pyrrole pyrylium quinoline reacted reaction reagent reduction resonance result ring salts Scheme shown similar sodium stable step strong Structure substitution Suggest sulfonic synthesis temperature thiophene treated treatment undergoes unit yield