The Centrosome in Cell Replication and Early Development

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Academic Press, Sep 26, 2000 - Science - 489 pages
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Centrosomes play an integral role in the growth of cells and the ultimate development of many animals, and sometimes plants. In addition to the normal growth of cells, centrosomes can also play a key role in the spread of cancer and are of increased interest to both the genetics and oncology communities. Volume 49 of Current Topics in Developmental Biology will present all known research surrounding the centrosome, across a variety of systems, will be well referenced, and speculate where the research is headed.
  • Discusses centrosomes and cancer, centrosomes and early development, and molecular biology of the centrosome
  • Heavily illustrated, with many color figures
  • Chapters written by international leaders in the field
 

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Contents

Chapter 1 The Centrosome and Parthenogenesis
1
Chapter 2 yTubulin
27
Chapter 3 yTubulin Complexes and Their Role in Microtubule Nucleation
55
Chapter 4 yTubulin of Budding Yeast
75
Architecture and Assembly of the Core Components
105
Chapter 6 The Microtubule Organizing Centers of Schizosaccharomyces pombe
133
Chapter 7 Comparative Structural Molecular and Functional Aspects of the Dictyostelium discoideum Centrosome
161
Chapter 8 Are There Nucleic Acids in the Centrosome?
187
Chapter 13 Regulating Centrosomes by Protein Phosphorylation
291
Chapter 14 The Role of the Centrosome in the Development of Malignant Tumors
313
Chapter 15 The CentrosomeAssociated AuroraIpllike Kinase Family
331
Chapter 16 Centrosome Reduction during Mammalian Spermiogenesis
343
Inheritance Assembly Replication and Developmental Roles
365
Chapter 18 The Centrosome in Drosophila Oocyte Development
385
Chapter 19 The Centrosome in Early Drosophila Embryogenesis
409
Chapter 20 Centrosome Maturation
449

Their Function and Structure
207
Chapter 10 Centriole Duplication and Maturation in Animal Cells
235
The Significance of the G1 Phase
251
Chapter 12 The Coordination of Centrosome Reproduction with Nuclear Events during the Cell Cycle
267

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About the author (2000)

Palazzo-University of Kansas, Lawrence, Kansas

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