Elements of Human CancerThis best-selling volume provides a broad overview of cancer from the basic biology and causes of human cancer through detailed discussion of the major types of cancer. A concluding chapter summarizes progress and discusses current and future directions in cancer research and treatment. |
Contents
What Is Cancer? | 4 |
Cancer and Age | 10 |
Benign and Malignant Neoplasms | 16 |
Invasion and Metastasis | 22 |
Key Terms | 28 |
Variation in Cancer Incidence Among Different Countries | 36 |
Alcohol | 42 |
Radiation | 44 |
Regulation of Gene Expression in Response to Growth Factors | 183 |
Regulation of Gene Expression by Steroids and Related Hormones | 185 |
Summary | 191 |
CANCER PREVENTION AND TREATMENT | 199 |
Dietary Factors | 206 |
The Questionable Importance of Synthetic Chemicals in | 213 |
Early Detection and Diagnosis | 220 |
Screening for Colorectal Cancer | 226 |
Medicines That Cause Cancer | 52 |
References and Further Reading | 58 |
Hepatitis B Virus | 64 |
Human TCell Lymphotropic Viruses | 70 |
Heredity and Cancer | 76 |
Racial and Familial Risk Factors | 84 |
Cell Growth and Differentiation | 91 |
Cell Division in Adults | 99 |
Summary | 105 |
Reduced Growth Factor Requirements of Cancer Cells | 112 |
Protease Secretion and Angiogenesis | 116 |
Oncogenes | 123 |
Differences Between Oncogenes and ProtoOncogenes | 131 |
Summary | 140 |
Hybrids Between Normal Cells and Cancer Cells | 146 |
Summary | 152 |
The Combined Roles of EpsteinBarr Virus and the cmyc | 161 |
Summary | 169 |
Oncogenes and Growth Factors | 175 |
Summary | 235 |
Radiation Therapy | 242 |
Drug Resistance and Combination Chemotherapy | 249 |
Immunotherapy | 255 |
Summary | 259 |
OVERVIEW OF MAJOR TYPES OF CANCER | 265 |
Acute Nonlymphocytic Leukemias | 271 |
Multiple Myeloma | 277 |
Brain Tumors | 283 |
References and Further Reading | 289 |
Colon and Rectum Cancer | 295 |
Urinary Cancers | 302 |
Stomach Cancer | 308 |
Thyroid Cancer | 311 |
PROSPECTS FOR THE FUTURE | 319 |
Progress in Understanding Cancer | 325 |
Glossary | 337 |
348 | |
Common terms and phrases
abnormal activity acute promyelocytic leukemia adult agents amplification associated bladder breast cancer Burkitt's lymphoma c-myc cancer cells cancer incidence cancer risk carcinogenesis carcinogens cause cell carcinoma cell division cell growth cell proliferation cell types cellular cervical carcinoma chemicals chemotherapy chromosome colon cancer colorectal Diagnosis dietary differentiation discussed in chapter disease early detection effects endometrial endometrial cancer epithelial Epstein-Barr virus estrogen example exposure extracellular frequently function gene expression genetic growth factor receptors hepatitis B virus hepatocellular carcinoma hormone human cancer inactivation increased induce infection inherited inhibit kinase leukemias and lymphomas lung cancer lymphocytes malignant melanoma metastasis mutations N-myc Natl neoplasms neuroblastomas normal cells oncogenes oncogenes and tumor papillomaviruses patients PDGF protein proto-oncogene radiation ras oncogenes regulation result retinoblastoma retinoic acid Risk Factors sarcoma skin cancers smoking stages stimulates surgery survival rates therapy thyroid tion tissue transformation translocation treatment tumor cells tumor development tumor suppressor gene viruses Wilms