Advances in Cancer Research
George F. Vande Woude, George Klein
Academic Press, Apr 22, 1999 - Medical - 249 pages
Volume 76 of Advances in Cancer Research continues the series' goal of publishing timely and authoritative reviews in the broad field of cancer research. Ruoslahti begins the volume with a review of fibronectin and its integrin receptors in cancer. Chapter 2 by Ganter and Lipsick discusses Myb and oncogenesis. Biscardi and colleagues present their research on c-Src, receptor tyrosine kinases, and human cancer in Chapter 3. Chapter 4 by Schulz covers epidemiology of Kaposi's sarcoma and associated herpesvirus/human herpesvirus 8. The consensus on synergism between cigarette smoke and other environmental carcinogens in the causation of lung cancer is reviewed by Reif and Heeren in Chapter 5. In Chapter 6, Breivik and Gaudernack discuss perspectives on carcinogenesis and natural selection in the genetics and epigenetics of colorectal cancer. Chapter 7 by Coulie and co-workers concludes the volume with a discussion of anti-tumor immunity at work in a melanoma patient.
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A-Myb Acad acid adhesion AIDS KS antibodies antigens apoptosis asbestos assays B-Myb binding Biochem blood donors c-Myb c-Src cancer cells Cancer Res carcinogenesis carcinogens carcinomas cDNA Cell Biol cell lines Chem classic KS colon colorectal colorectal cancer cortactin CTL clones detected DNA methylation DNA-binding domain EMBO encoded expression extracellular fibronectin gene genetic growth factor HER1 HER2 HIV-infected homosexual Hu_c-Myb ch_c-Myb human tumors inhibit integrin interaction kinase activity Klempnauer KSHV KSHV DNA KSHV infection LANA Lennette levels ligand Lipsick lung cancer lytic matrix MEL.A cells MEL.B melanoma metastasis molecules mutations Myb proteins Natl Nature London neoplastic Oncogene overexpression pathway PDGF peptide phosphorylation Proc promoter protein radon regulation role Ruoslahti sequence SH2 domain signaling smoking specific studies suggest synergism tion tissue transcriptional activation transformation tumor tumor cells tyrosine kinases v-Myb variants Virol vitro vivo Whitby