The Analysis Of Drugs Of Abuse: An Instruction Manual: An Instruction ManualProvides a self-teaching reference text for forensic chemistry laboratories and law enforcement agencies world-wide. The text includes sections on the importance of physical examinations of drugs and their wrappings; and the use of gas and high-performance chromatography. |
Contents
| 7 | |
| 7 | |
| 7 | |
| 7 | |
16 References and further reading | 19 |
Physical description of drugs of abuse 21 Introduction | 20 |
22 Cannabis sativa L and products | 20 |
223 Hash Oil | 23 |
64 Quantification of samples and preparation of calibration curves | 96 |
641 Single point estimates | 97 |
Y mX + c | 98 |
643 Linear regression | 99 |
65 Diode array detection | 102 |
66 Student exercises | 105 |
6612 Quantification of diamorphine in an illicit sample of heroin | 106 |
6622 Reversed phase chromatography and ion suppression cannabinoids | 107 |
23 Lysergic acid diethylamide LSD | 25 |
24 Hallucinogens of fungal origin | 28 |
25 Hallucinogens from cacti | 29 |
262 Diamorphine | 30 |
27 Coca leaf and cocaine | 32 |
28 The amphetamines | 33 |
29 Methaqualone and mecloqualone | 34 |
210 Barbiturates | 35 |
211 Benzodiazepines | 36 |
2121 Cannabis plant material | 37 |
Presumptive tests for drugs of abuse 31 Introduction | 41 |
321 Cannabis and products | 43 |
322 Lysergic acid diethylamide psilocybin and psilocin | 44 |
3241 Cobalt isothiocyanate | 45 |
325 The amphetamines | 46 |
3271 The Zimmerman test | 47 |
34 References | 49 |
Thin layer chromatography of drugs of abuse 41 Introduction | 51 |
42 Spray reagents commonly used in drug analysis | 55 |
422 Ehrlichs reagent | 56 |
431 Cannabis and its products | 58 |
433 Cocaine and surrogates | 59 |
Gas chromatography of drugs of abuse 51 Introduction | 63 |
52 Interpretation of chromatographic data | 76 |
524 Quantification | 78 |
531 Kovats indices and opiate drugs | 81 |
532 Gas chromatography of opiate drugs using temperature programming | 82 |
534 Cannabinoids | 83 |
537 Benzodiazepines | 85 |
High performance liquid chromatography of drugs of abuse 61 Introduction | 87 |
62 The separation process | 91 |
622 Reversed phase chromatography | 94 |
6222 Ion pairing systems and reversed phase chromatography | 95 |
67 References | 108 |
Ultra violet spectroscopy of drugs of abuse 71 Introduction | 109 |
72 Recording of an ultra violet absorption spectrum | 110 |
75 Student exercises | 113 |
Infra red spectroscopy of drugs of abuse 81 Introduction | 115 |
82 Sample preparation | 116 |
821 The gas phase | 117 |
83 The dispersive infra red spectrometer | 118 |
842 Amino imine and amide groups | 120 |
845 The carbonyl group | 121 |
851 The opiate drugs 8511 Morphine | 122 |
8513 Diamorphine | 123 |
8514 Codeine | 124 |
8515 Acetylcodeine | 125 |
853 Cocaine | 127 |
855 Amphetamines | 129 |
856 Benzodiazepines exemplified by Medazepam | 130 |
86 Student exercises | 131 |
88 Library searches | 133 |
810 References | 134 |
Gas chromatography mass spectroscopy of drugs of abuse 91 Introduction | 135 |
92 The gas chromatograph mass spectrometer GCMS | 136 |
9211 Electron impact mass spectrometry | 137 |
9212 Chemical ionization mass spectroscopy | 138 |
9214 Advantages and disadvantages of mass spectroscopy | 139 |
931 Total ion chromatograms | 140 |
9322 Isotope peaks | 144 |
9323 Selected ion monitoring | 145 |
| 146 | |
941 Underivatised drugs 9411 Opiate drugs | 150 |
9412 Cocaine and metabolites | 151 |
9422 Cannabinoid drugs | 153 |
Other editions - View all
The Analysis Of Drugs Of Abuse: An Instruction Manual: An Instruction Manual M D Cole,B Caddy Limited preview - 1994 |
The Analysis Of Drugs Of Abuse: An Instruction Manual: An Instruction Manual M D Cole No preview available - 1994 |
Common terms and phrases
absorbance absorption acetylcodeine acid amphetamines analysis of drugs analytes aryl barbiturate drugs barbiturates benzodiazepines bond C-H stretch calibration curve cannabinoids Cannabis resin Cannabis sativa carbonyl carrier gas chromatographic cm-¹ cm¹ cocaine codeine colour reactions column components compounds concentration containing controlled substances derivatisation detection detector deuterated diamorphine drug analysis drug chemist drugs of abuse ecgonine electrons elution order employed ester example Forensic Science gas chromatography heroin HPLC HPLC system identify illicit Infra red spectroscopy infra red spectrum injection interaction Kovat's Indices linear Mandelin mass spectrometer mass spectrum methanol Methaqualone method mixture mobile phase molecules morphine nitrogen obtained opiate opiate drugs peak area peak height plant material polar prepared presumptive tests psilocin quantification reagent retention Reversed phase chromatography Rf values seizure silica gel solution solvent specified in paragraph spectra stationary phase Student exercises substance specified substituents technique temperature trichomes UV light wavelength wavenumbers whilst
Popular passages
Page 8 - Schedule. 4. Any preparation or other product containing a substance or product for the time being specified in any of paragraphs 1 to 3 of this Part of this Schedule, not being a preparation falling within paragraph 6 of Part I of this Schedule. PART III CLASS C DRUGS 1. The following substances, namely: (a)87 Alprazolam...
Page 10 - N-alkyl-amethylphenethylamine, a-ethylphenethylamine, or an N-alkyl-a-ethylphenethylamine by substitution in the ring, to any extent with alkyl, alkoxy, alkylenedioxy or halide substituents, whether or not further substituted in...
Page 10 - N-oxide or of a qua ternary base. 2. Any stereoisomeric form of a substance for the time being specified in paragraph 1 above not being dextromethorphan or dextrorphan. 3. Any ester or ether of a substance for the time being specified in paragraph 1 or 2 above (not being a substance for the time being specified in Part n of this Schedule).
Page 12 - TV-alky! derivatives of lysergamide. Mescaline. Metazocine. Methadone. Methadyl acetate. Methyldesorphine. Methyldihydromorphine (6-methyldihydromorphine). Metopon. Morpheridine. Morphine. Morphine methobromide, morphine TV-oxide and other pentavalent nitrogen morphine derivatives.
Page 9 - Schedule. 3. Any salt of a substance for the time being specified in paragraph 1 or 2 of this Part of this Schedule. 4. Any preparation or other product containing a substance for the time being specified in any of paragraphs 1 to 3 of this Part of this Schedule.
Page 7 - Allylprodine. Alphacetylmethadol. Alphameprodine. Alphamethadol. Alphaprodine. Anileridine. Benzethidine. Benzylmorphine (3-benzylmorphine). Betacetylmethadol. Betameprodine. Betamethadol. Betaprodine. Bezitramide. Bufotenine. Cannabinol. except where contained in cannabis or cannabis resin. Cannabinol derivatives. Clonitazene. Coca leaf. Cocaine. Desomorphine. Dextromoramide. Diamorphine. Diampromide. Diethylthiambutene.
Page 10 - ZipeproP (b) any 5,5 disubstituted barbituric acid.32 2. Any stereoisomeric form of a substance for the time being specified in paragraph 1 of this part of this Schedule. 3. Any salt of a substance for the time being specified in any of paragraph 1 or 2 of this Part of this Schedule.
Page 8 - Levorphanol Lysergamide Lysergide and other N-alkyl derivatives of lysergamide Mescaline Metazocine Methadone Methadyl acetate Methyldesorphine Methyldihydromorphine (6-methyldihydromorphine...
Page 11 - ... (b) any compound (not being a compound for the time being specified in sub-paragraph (a) above) structurally derived from tryptamine or from a ring-hydroxy tryptamine by substitution at the nitrogen atom of the...