Asthma and COPD: Basic Mechanisms and Clinical Management

Front Cover
Peter J. Barnes, Jeffrey M. Drazen, Stephen I. Rennard, Neil C. Thomson
Academic Press, Oct 30, 2008 - Medical - 896 pages
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.

  • Each chapter considers Asthma and COPD in side-by-side contrast and comparison - not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management
  • Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD
  • Most extensive reference to primary literature on both Asthma and COPD in one source.
  • Easy-to-read summaries of the latest advances alongside clear illustrations
 

Contents

DEFINITIONS EPIDEMIOLOGY AND GENETICS OF ASTHMA AND COPD
1
PHYSIOLOGY AND PATHOLOGY OF ASTHMA AND COPD
53
INFLAMMATORY CELLS AND EXTRACELLULAR MATRIX
111
INFLAMMATORY MEDIATORS AND PATHWAYS
275
PATHOGENIC MECHANISMS IN ASTHMA AND COPD
399
TRIGGERS OF ASTHMA AND COPD
443
CLINICAL ASSESSMENT OF ASTHMA AND COPD
523
THERAPIES FOR ASTHMA AND COPD
579
CLINICAL MANAGEMENT OF ASTHMA AND COPD
761
INDEX
855
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About the author (2008)

Peter Barnes is Professor of Thoracic Medicine at the National Heart and Lung Institute, Head of Respiratory Medicine at Imperial College and Honorary Consultant Physician at Royal Brompton Hospital, London. He qualified at Cambridge and Oxford Universities was appointed to his present post in 1987. He has published over 1000 peer-review papers on asthma, COPD and related topics and has edited over 40 books. He is also amongst the top 50 most highly cited researchers in the world and has been the most highly cited clinical scientist in the UK and the most highly cited respiratory researcher in the world over the last 20 years. He was elected a Fellow of the Royal Society in 2007, the first respiratory researcher for over 150 years. He is currently a member of the Scientific Committee of the WHO/NIH global guidelines on asthma (GINA) and COPD (GOLD). He also serves on the Editorial Board of over 30 journals and is currently an Associate Editor of Chest and respiratory Editor of PLoS Medicine. He has given several prestigious lectures, including the Amberson Lecture at the American Thoracic Society and the Sadoul Lecture at the European Respiratory Society. Neil Thomson is Professor of Respiratory Medicine at the University of Glasgow, Head of Respiratory Medicine within the Division of Immunology, Infection & Inflammation and Honorary Consultant at Gartnavel General Hospital, Glasgow. He graduated from the University of Glasgow and undertook postgraduate training in Glasgow, London and McMaster University, Canada. He is a former member of the Committee for Safety of Medicine and former Chair of the Scientific Committee of the British Lung Foundation. He has co-edited several textbooks on asthma and COPD and published over 150 peer-reviewed papers on asthma. His current research interests include corticosteroid insensitivity in smokers with asthma, biomarkers in asthma and COPD and assessment of novel treatments for asthma.