Asthma and COPD: Basic Mechanisms and Clinical ManagementPeter J. Barnes, Jeffrey M. Drazen, Stephen I. Rennard, Neil C. Thomson The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.
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Contents
DEFINITIONS EPIDEMIOLOGY AND GENETICS OF ASTHMA AND COPD | 1 |
PHYSIOLOGY AND PATHOLOGY OF ASTHMA AND COPD | 53 |
INFLAMMATORY CELLS AND EXTRACELLULAR MATRIX | 111 |
INFLAMMATORY MEDIATORS AND PATHWAYS | 275 |
PATHOGENIC MECHANISMS IN ASTHMA AND COPD | 399 |
TRIGGERS OF ASTHMA AND COPD | 443 |
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Common terms and phrases
activation airflow airway airway epithelial airway hyperresponsiveness airway inflammation airway responsiveness airway smooth muscle allergen Allergy Allergy Clin Immunol alveolar antigen apoptosis associated asthma asthma and COPD Barnes PJ bronchial bronchoconstriction CD8+ Cell Mol Biol chemokines chronic bronchitis chronic obstructive pulmonary cigarette smoke Clin Invest clinical collagen COPD COPD patients cytokines dendritic cells effects elastin emphysema endothelial eosinophils epithelial cells epithelium exacerbations exhaled exposure expression fibroblasts fibrosis gene genetic growth factor increased induced infection inflammation inflammatory cells inhaled inhibition inhibitors integrins interactions interleukin kinase leukotriene lung function macrophages mast cells mechanisms mediators mice molecules monocytes mucin mucus neutrophils nitric oxide normal obstructive pulmonary disease oxidative stress pathogenesis pathways patients with COPD phenotype Physiol production protein proteinases receptor regulation release Respir Cell Mol Respir Crit respiratory Rev Respir role signaling smooth muscle smooth muscle cells sputum studies symptoms T-cells TGF-ẞ Thorax tion tissue TNF-a vascular vitro vivo