DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology

Front Cover
Lippincott Williams & Wilkins, Jan 7, 2015 - Medical - 2280 pages
DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues
 

Contents

Introduction
Epidemiology
Second Cancers
Chronic Lymphocytic Leukemia
Pathophysiology
EFFECTS OF TREATMENT
Etiology
Pathology
Treatment
Metabolic Emergencies
Lactic Acidosis and Cancer
Leptomeningeal Metastases
Metastatic Cancer to the Lung
Presentation and Diagnosis of Pulmonary Metastases
Ablative Therapies
Conclusion

Malignant Pleural and Pericardial Effusions
Symptom Management
Clinical Presentation
Differential Diagnosis
Mutational Complementation Groups in Acute Leukemias
Diagnosis
Pathogenesis
Treatment
Prognosis
Leukemias and Lymphomas of Childhood
Supportive Care
LYMPHOMAS IN ADULTS
Molecular Pathogenesis of BNHL
Molecular Pathogenesis of TCell NonHodgkin Lymphoma
Hodgkins Lymphoma
Differential Diagnosis
EarlyStage Hodgkins Lymphoma
AdvancedStage Hodgkins Lymphoma
Special Circumstances
Pulmonary Toxicity
NonHodgkins Lymphoma
The Principles of the World Health
Specific Disease Entities
Mature TCell and Natural Killer Cell Neoplasms
Cutaneous Lymphomas
Diagnosis and Staging
Clinical Evaluation of Patients with Cutaneous Lymphoma
Systemic Therapy for Mycosis Fungoides and the Sézary Syndrome
Other Cutaneous Lymphomas
Diagnosis and Prognostic Factors
Primary Central Nervous System Lymphoma
LEUKEMIAS AND PLASMA CELL
Mutations that Target CoreBinding Factor
Chromosomal Translocations that Target the MLL Gene
Chromosomal Translocations that Result in Overexpression of cMYC
Mutations in Tumor Suppresenes
Partow Kebriaei Marcos de Lima Elihu H Estey
Molecular Biology of Chronic Leukemias
Acknowledgments
Brian J Druker and David Marin
Prognostic Factors
Advanced Phase Disease
William G Wierda and Susan M O
New and Novel Treatments for Chronic Lymphocytic Leukemia
Myelodysplastic Syndromes
Clinical Presentation
Plasma Cell Neoplasms
Drug Resistance
OTHER CANCERS
Studies of Molecular Gene Expression Tumor Profiling Assays in Cancer
Clinical Features and Evaluation
Special Issues in Carcinoma of Unknown Primary Site
Benign and Malignant Mesothelioma
Alterations of Oncogenes in Mesothelioma
Pathology of Mesothelioma
Diagnostic Approach for Presumed Mesothelioma
Surgery for Pleural Mesothelioma
Evolution of Lung Sparing Approaches for Macroscopic Complete
Novel Therapeutic Approaches
Peritoneal Metastases and Peritoneal Mesothelioma
Appendiceal Malignancy
Diffuse Malignant Peritoneal Mesothelioma
Sarcomatosis
Intraocular Melanoma
Ophthalmic Diagnosis
Diagnosis of Uveal Melanoma Metastasis
IMMUNOSUPPRESSION RELATED
Lymphoid Tumors in Patients with
Human PapillomavirusAssociated Cancer in HIV Infection
TransplantationRelated Malignancies
Lymphomas
ONCOLOGIC EMERGENCIES
Increased Intracranial Pressure
Metastatic Cancer to the Liver
Hepatic Neuroendocrine Carcinoma Metastases
Metastatic Cancer to the Bone
Denosumab
Systemic Radionuclides
Mechanical Stability and Fracture Risk
Nguyen and Eddie W Manning III
Malignant Pericardial Effusion
Diagnosis
Paraneoplastic Syndromes
Paraneoplastic Hematologic Syndromes
STEM CELL TRANSPLANTATION
Indications For Autologous Hematopoietic Cell Transplantation
Autologous Hematopoietic Cell Transplantation for Rarer Plasma Cell
Autologous Stem Cell Transplantation
Transplantation
Complications of Allogeneic Hematopoietic Cell Transplantation
Graft Failure
MANAGEMENT OF ADVERSE
Prevention of Infections
DIAGNOSIS AND MANAGEMENT OF INFECTIOUS DISEASES
Multidrug Resistant Organisms of Interest in Oncology
Introduction
Cancer Associated Thrombosis
Prevention of CancerAssociated Thrombosis
Nausea And Vomiting
Nausea and Vomiting Syndromes
Antiemetic Treatment by Clinical Setting
Conclusion
RadiationInduced Mucositis
Biologic Response Modifiers
Diane E Stover Caroline M Gulati Alexander I
Cardiac Toxicity
Conclusion
Treatment
Effects of Cytotoxic Agents on Adult
Effects of Cytotoxic Agents on Children
Pharmacologic Attempts at Preserving Fertility in
Fatigue
Lois B Travis Smita Bhatia James M Allan Kevin C
Risk of Second Malignancy in Patients with Selected Primary Cancers
Pediatric Malignancies
Comments
Neurocognitive Effects
Treatment of Cognitive Dysfunction
Definition of Survivorship and Scope of the Problem
Educational Considerations
Enhancing Research
P A R T V I
Common Pain Syndromes
Management of Cancer Pain
Psychological Approaches
Neuropharmacologic Approaches
Nutritional Support
Nutrition Screening and Assessment
Effect of Nutrition Support on Tumor Growth
Sexual Problems
Cancers that Affect Men and Women
Cancer in Children and Young Adults
Psychological Issues
Coping
Communicating News to the Cancer Patient
Specialized Care of the Terminally
Wounds
Bleeding
Complications of Cancer and its Treatment
Musculoskeletal Complications of Cancer and Cancer Treatment
Rehabilitation Interventions
Integrative Therapies
Standardization and Quality
Summary
Index
Spinal Cord Compression

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