DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of OncologyDeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 10th edition has garnered universal acclaim as the world’s definitive, standard-setting oncology reference. More than 400 respected luminaries explore today’s most effective strategies for managing every type of cancer by stage of presentation - discussing the role of all appropriate therapeutic modalities as well as combined-modality treatments. This multidisciplinary approach will help your cancer team collaboratively face the toughest clinical challenges and provide the best possible care for every cancer patient. Access the complete contents online or on your mobile device, with quarterly updates reflecting late-breaking developments in cancer care, free for the first year on LWW Health Library. Take full advantage of the latest advances with brand-new chapters on Hallmarks of Cancer, Molecular Methods in Cancer, Oncogenic Viruses, Cancer Screening, and new sections on Genetic testing and counseling for cancer, plus comprehensive updates throughout – including coverage of the newest biologic therapies. Make optimal, well-coordinated use of all appropriate therapies with balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist in each major treatment chapter. Review the latest molecular biology knowledge for each type of cancer and its implications for improved management. Make the best decisions on cancer screening and prevention, palliative care, supportive oncology, and quality-of-life issues |
Contents
Introduction | |
Epidemiology | |
Second Cancers | |
Chronic Lymphocytic Leukemia | |
Pathophysiology | |
EFFECTS OF TREATMENT | |
Etiology | |
Pathology | |
Treatment | |
Metabolic Emergencies | |
Lactic Acidosis and Cancer | |
Leptomeningeal Metastases | |
Metastatic Cancer to the Lung | |
Presentation and Diagnosis of Pulmonary Metastases | |
Ablative Therapies | |
Conclusion | |
Malignant Pleural and Pericardial Effusions | |
Symptom Management | |
Clinical Presentation | |
Differential Diagnosis | |
Mutational Complementation Groups in Acute Leukemias | |
Diagnosis | |
Pathogenesis | |
Treatment | |
Prognosis | |
Leukemias and Lymphomas of Childhood | |
Supportive Care | |
LYMPHOMAS IN ADULTS | |
Molecular Pathogenesis of BNHL | |
Molecular Pathogenesis of TCell NonHodgkin Lymphoma | |
Hodgkins Lymphoma | |
Differential Diagnosis | |
EarlyStage Hodgkins Lymphoma | |
AdvancedStage Hodgkins Lymphoma | |
Special Circumstances | |
Pulmonary Toxicity | |
NonHodgkins Lymphoma | |
The Principles of the World Health | |
Specific Disease Entities | |
Mature TCell and Natural Killer Cell Neoplasms | |
Cutaneous Lymphomas | |
Diagnosis and Staging | |
Clinical Evaluation of Patients with Cutaneous Lymphoma | |
Systemic Therapy for Mycosis Fungoides and the Sézary Syndrome | |
Other Cutaneous Lymphomas | |
Diagnosis and Prognostic Factors | |
Primary Central Nervous System Lymphoma | |
LEUKEMIAS AND PLASMA CELL | |
Mutations that Target CoreBinding Factor | |
Chromosomal Translocations that Target the MLL Gene | |
Chromosomal Translocations that Result in Overexpression of cMYC | |
Mutations in Tumor Suppresenes | |
Partow Kebriaei Marcos de Lima Elihu H Estey | |
Molecular Biology of Chronic Leukemias | |
Acknowledgments | |
Brian J Druker and David Marin | |
Prognostic Factors | |
Advanced Phase Disease | |
William G Wierda and Susan M O | |
New and Novel Treatments for Chronic Lymphocytic Leukemia | |
Myelodysplastic Syndromes | |
Clinical Presentation | |
Plasma Cell Neoplasms | |
Drug Resistance | |
OTHER CANCERS | |
Studies of Molecular Gene Expression Tumor Profiling Assays in Cancer | |
Clinical Features and Evaluation | |
Special Issues in Carcinoma of Unknown Primary Site | |
Benign and Malignant Mesothelioma | |
Alterations of Oncogenes in Mesothelioma | |
Pathology of Mesothelioma | |
Diagnostic Approach for Presumed Mesothelioma | |
Surgery for Pleural Mesothelioma | |
Evolution of Lung Sparing Approaches for Macroscopic Complete | |
Novel Therapeutic Approaches | |
Peritoneal Metastases and Peritoneal Mesothelioma | |
Appendiceal Malignancy | |
Diffuse Malignant Peritoneal Mesothelioma | |
Sarcomatosis | |
Intraocular Melanoma | |
Ophthalmic Diagnosis | |
Diagnosis of Uveal Melanoma Metastasis | |
IMMUNOSUPPRESSION RELATED | |
Lymphoid Tumors in Patients with | |
Human PapillomavirusAssociated Cancer in HIV Infection | |
TransplantationRelated Malignancies | |
Lymphomas | |
ONCOLOGIC EMERGENCIES | |
Increased Intracranial Pressure | |
Metastatic Cancer to the Liver | |
Hepatic Neuroendocrine Carcinoma Metastases | |
Metastatic Cancer to the Bone | |
Denosumab | |
Systemic Radionuclides | |
Mechanical Stability and Fracture Risk | |
Nguyen and Eddie W Manning III | |
Malignant Pericardial Effusion | |
Diagnosis | |
Paraneoplastic Syndromes | |
Paraneoplastic Hematologic Syndromes | |
STEM CELL TRANSPLANTATION | |
Indications For Autologous Hematopoietic Cell Transplantation | |
Autologous Hematopoietic Cell Transplantation for Rarer Plasma Cell | |
Autologous Stem Cell Transplantation | |
Transplantation | |
Complications of Allogeneic Hematopoietic Cell Transplantation | |
Graft Failure | |
MANAGEMENT OF ADVERSE | |
Prevention of Infections | |
DIAGNOSIS AND MANAGEMENT OF INFECTIOUS DISEASES | |
Multidrug Resistant Organisms of Interest in Oncology | |
Introduction | |
Cancer Associated Thrombosis | |
Prevention of CancerAssociated Thrombosis | |
Nausea And Vomiting | |
Nausea and Vomiting Syndromes | |
Antiemetic Treatment by Clinical Setting | |
Conclusion | |
RadiationInduced Mucositis | |
Biologic Response Modifiers | |
Diane E Stover Caroline M Gulati Alexander I | |
Cardiac Toxicity | |
Conclusion | |
Treatment | |
Effects of Cytotoxic Agents on Adult | |
Effects of Cytotoxic Agents on Children | |
Pharmacologic Attempts at Preserving Fertility in | |
Fatigue | |
Lois B Travis Smita Bhatia James M Allan Kevin C | |
Risk of Second Malignancy in Patients with Selected Primary Cancers | |
Pediatric Malignancies | |
Comments | |
Neurocognitive Effects | |
Treatment of Cognitive Dysfunction | |
Definition of Survivorship and Scope of the Problem | |
Educational Considerations | |
Enhancing Research | |
P A R T V I | |
Common Pain Syndromes | |
Management of Cancer Pain | |
Psychological Approaches | |
Neuropharmacologic Approaches | |
Nutritional Support | |
Nutrition Screening and Assessment | |
Effect of Nutrition Support on Tumor Growth | |
Sexual Problems | |
Cancers that Affect Men and Women | |
Cancer in Children and Young Adults | |
Psychological Issues | |
Coping | |
Communicating News to the Cancer Patient | |
Specialized Care of the Terminally | |
Wounds | |
Bleeding | |
Complications of Cancer and its Treatment | |
Musculoskeletal Complications of Cancer and Cancer Treatment | |
Rehabilitation Interventions | |
Integrative Therapies | |
Standardization and Quality | |
Summary | |
Index | |
Spinal Cord Compression | |
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Common terms and phrases
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