Research Projects in Dry Eye SyndromeH. Brewitt Dry eye is one of the most common disorders encountered in ophthalmological practice. Its symptoms cause considerable discomfort and substantially reduce the patient’s quality of life. As it is a complex and multifactorial condition, research investigating dry eye is a matter of great interest all over the world.In this book, the wide range of current basic and clinical research in dry eye and correlated ocular surface diseases is presented by scientists from Germany, Austria and the USA. These renowned authors provide clear and extensive descriptions of their projects, enabling scientists and clinical ophthalmologists to quickly bring themselves up to date with cutting edge research in this field.This overview of research into the pathogenesis and clinical treatment of dry eye is a must for all ophthalmologists dealing with this syndrome and looking to increase their knowledge base. |
Contents
| 1 | |
Cationic Amino Acid Transporters and βDefensins in Dry Eye Syndrome | 12 |
Antimicrobial Peptides as a Major Part of the Innate Immune Defense at the Ocular Surface | 16 |
Regulation of the Inflammatory Component in Chronic Dry Eye Disease by the EyeAssociated Lymphoid Tissue EALT | 23 |
Intravital Multidimensional RealTime Imaging of the Conjunctival Immune System | 40 |
Generation of Two and ThreeDimensional Lacrimal Gland Constructs | 49 |
Midterm Results of Cultivated Autologous and Allogeneic Limbal Epithelial Transplantation in Limbal Stem Cell Deficiency | 57 |
Laser Scanning Confocal Microscopy for Conjunctival Epithelium Imaging | 71 |
The ex vivo Eye Irritation Test | 93 |
The Lid Margin Is an Underestimated Structure for Preservation of Ocular Surface Health and Development of Dry Eye Disease | 108 |
Diagnostic Markers of Sjögrens Syndrome | 123 |
Hyperosmolarity of the Tear Film in Dry Eye Syndrome | 129 |
Details of Its Mechanism of Action | 139 |
| 148 | |
| 149 | |
An Approach to Understanding Seasonal NonAllergic Conjunctivitis | 83 |
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Common terms and phrases
allogeneic amniotic membrane AMPs antibodies antigens antimicrobial peptides artificial tears autologous Basel Biol Brewitt H CALT clinical confocal microscopy conjunctival conjunctival epithelium corneal epithelium corneal surface cytokines defensins Department of Ophthalmology detected dry eye conditions dry eye disease Dry Eye Syndrome duct E-Mail epithelial cells evaporation EVEIT Exp Eye Res eye-associated follicles function Germany goblet cells healing human conjunctiva imaging impression cytology increased incubated induced inflammation inflammatory cytokines Invest Ophthalmol Karger keratoconjunctivitis sicca Knop lacrimal gland lacrimation interval laser layer lid margin lid wiper limbal epithelium limbal stem cell lipid logMAR LSCM lymphocytes lymphoid tissue meibomian gland mg/ml mucins Ocul ocular surface ocular surface disease ofthe Ophthalmol Vis Sci Ophthalmology osmolarity Paulsen Pflugfelder SC pollen extract proteins rhTFF3 secretory sicca syndrome Sjögren’s syndrome staining structure studies symptoms Systane tear film tear film osmolarity tear fluid Tearlab TFF3 tion transplantation trefoil factor two-photon microscopy vitro