Ogilvie, James P., discusses the determination of sucrose in beetsugar factory products by Clerget's process, using invertase as hydrolyst.-J. Soc. Chem. Ind. 1911, v. 30, pp. 62-64.

v. Fillinger, Franz, describes a new method for the estimation of sugar by combining the advantages of the Pavy and of the Bang methods.-Ztschr. Unters. Nahr. u. Genussm. 1911, v. 22, pp. 606

607.

Anderson, A. C. (Tidskr. Kemie, Farm. Terapi, 1910, 232-237), discusses the stability of the standard solutions used in Bang's method for sugar determination. Chem. Abstr. 1911, v. 5, p. 1380. Walker, Percy H., presents a correction in connection with the work on the unification of reducing sugar methods, published in Bureau of Chemistry Bulletin No. 107.-Circ. Bur. Chem. U. S. Dept. Agric. 1911, No. 82, p. 6.

Yoder, P. A., outlines a polarimetric method for the estimation of malic acid in cane and maple sugar products.-Ztschr. Unters. Nahr. u. Genussm. 1911, v. 22, pp. 329–353.

Bierry and Ranc outline a method for the detection of small quantities of glucose and galactose in the presence of lactose.Compt. rend. Soc. Biol. 1911, v. 71, p. 440.

See also under Saccharum and under Clinical Tests.

11. CLINICAL TESTS.

Heyl, Georg, discusses the reagents and volumetric solutions for clinical testing, added to the Ph. Germ. V, and outlines methods for using them.-Apoth.-Ztg. 1911, v. 26, pp. 520-521, 531-533.

A book review of the Ph. Germ. V (Lancet, 1911, v. 180, p. 119) states that an interesting addition to the present edition has been made in the inclusion among the appendices of a list of formulæ and reagents for preparing tests employed in biological analyses.

Beringer, George M., thinks the list of reagents and volumetric solutions for medico-chemical examinations is one of the most commendable features of the Ph. Germ. V.-Proc. New Jersey Pharm. Assoc. 1911, p. 82. See also Am. J. Pharm. 1911, v. 83, p. 335.

Richter, R., discusses the method of applying the reagents, included in the Ph. Germ. V., for clinical testing.-Pharm. Ztg. 1911, v. 56, pp. 229–230.

Wulff, C., comments on the analytical tests of the Ph. Germ. V and points out that many of the substances enumerated are not described or standardized beyond the general requirement that the substance must be pure.-Ber. pharm. Gesellsch. 1911, v. 21, pp.

206-207.

Voelcker, Edwin B., discusses the drug store laboratory and the uses to which it can be put.-Proc. Texas Pharm. Assoc. 1911, pp. 113-116.

Fisher, Jessie Weston, discusses the interpretation of laboratory findings.-Boston M. & S. J. 1911, v. 165, pp. 9-13.

Schwabe, Emil, describes and illustrates a sedimentation tube for microscopical analyses. Chem. Ztg. 1911, v. 35, p. 577.

Stephens, G. Arbor, describes a salivary reaction in diabetes mellitus. Brit. M. J. 1911, v. 1, p. 993.

An editorial (N. York M. J. 1911, v. 93, p. 584) discusses the phlorrhizin test of hepatic and renal insufficiency, with special reference to the recent work of Rebattu (Thèse de Lyon, 1910).

An unsigned article (Drug. Circ. 1911, v. 55, p. 130 ff.), entitled physiological laboratory notes, calls attention to a number of modifications and changes in clinical tests.

For a review of the progress made in the field of physiological tests during the year 1910, see Pharm. Prax. 1911, v. 10, pp. 65-79, 157-172.

Dennstedt, M., reviews the progress made in the field of forensic chemistry.-Ber. deutsch. chem. Gesellsch. 1911, v. 44, pp. 5-38. See also Oesterr. Chem.-Ztg. 1911, v. 14, pp. 27-29, and Pharm. Post, 1911, v. 44, pp. 141-143.

Magnin, Georges, presents a new method for the destruction of organic matter by bromine, especially applicable in toxicology.— J. Pharm. et Chim. 1911, v. 4, pp. 302-306.

Breteau, Pierre, presents a method for the complete destruction of organic matters in the detection of mineral poisons. Bull. Soc. chim. France, 1911, v. 9, pp. 615-620. Also J. Pharm. et Chim. 1911, v. 3, pp. 430-436, and Répert. pharm. 1911, v. 23, p. 302.

Garnier, Léon, calls attention to a source of error in the toxicologic detection of mercury derivatives, and urges special precautions to avoid the loss and even complete disappearance of the metallic poisons in the course of evaporation on the water bath.-J. Pharm. et Chim. 1911, v. 3, pp. 13-15.

de Ridder, G., discusses at some length the chemistry and hygiene of milk, its contamination and adulteration.-J. Pharm. Anvers, 1911, v. 67, pp. 81-98; 121-135.

Mayer, Joseph L., presents some simple, accurate methods of milk analysis.-Drug. Circ. 1911, v. 55, pp. 185–187; also Am. Druggist, 1911, v. 58, pp. 211–212.

Frouin, Albert, contributes a note on the use of saponin to homogenize samples of milk intended for analysis.-Bull. sc. pharmacol. 1911, v. 18, p. 697.

Backe, Wiborg, and Röer present a paper on the analysis of sweetened condensed milk.-Analyst, 1911, v. 36, pp. 138-141. Richmond, H. Droop, contributes a note on the degree of accuracy with which proteins can be estimated in milk by aldehyde titration.— Ibid. pp. 9-12.

Miller, E. Holl, contributes a note on the gravimetric estimation of phosphorus in milk.—Ibid. pp. 579–583.

Richmond, H. Droop, presents a tabulated statement of the average composition of milk during 1910 from the laboratory of the Aylesbury Dairy Company.-Ibid. pp. 390–392.

URINE.

Bouchez and Lambling discuss the composition of normal human urine. Compt. rend. Soc. Biol. 1911, v. 71, pp. 435–438, 486–488. Leven, G., presents a brief note on normal urine, to which Desesquelle replies. Bull. sc. pharmacol. 1911, v. 18, Annexes, pp. 250,

251.

Utz presents a review of recent literature relating to the detection of abnormal constituents in urine.-Pharm. Post, 1911, v. 44, pp.

417-420.

Chambers, Graham, contributes a brief note on his observations on the urines of Marathon runners, with a summary of the important findings. Brit. M. J. 1911, v. 1, p. 490.

Kojo, Kenji, discusses the differences in the composition of the urine of healthy and carcinomatous patients.-Ztschr. physiol. Chem. 1911, v. 73, pp. 416–433.

Outis presents an abstract of a lecture by F. Cathelin on the analysis of the separate urines from the two kidneys.-Bull. sc. pharmacol. 1911, v. 18, Annexes, pp. 111-114.

Lawrence, Charles H., describes and illustrates a method of collecting urine from female infants.-Boston M. & S. J. 1911, v. 164, p. 309.

Fisher, Jessie Weston, in discussing the interpretation of laboratory findings, points out that exact methods are essential for the diagnosis of any disease based on the study of the urine.-Ibid. v. 165, pp. 12–13.

Little, E. Graham, discusses the value of urinary examinations in dermatologic practice, with special reference to the Joulie reactions. Practitioner, 1911, v. 87, pp. 43–60.

Klein, Fred, contributes an article on urinalysis for the pharmacist. Pract. Drug. 1911, v. 29, Aug., p. 33, and Sept., p. 33.

Kahn, Joseph, endorses the recommendation that reagents used in urinalysis be added to the U. S. P.-Proc. New York Pharm. Assoc. 1911, p. 85.

Boucher, Volcy, presents a note on the graphic representation of the principal results of urinalysis, illustrated by a chart-Bull. sc. pharmacol. 1911, v. 18, p. 354.

Utz presents a comprehensive review of the progress made in the examination of urine during the year 1910.-Pharm. Post, 1911, v. 44, pp. 397-401, 406-408, 417-420.

Meillére, G., presents a general review of recent work in medical chemistry relating to urinology (1909-1910)-J. Pharm. et. Chim. 1911, v. 3, pp. 441-452, 541-548.

Gauvin, R., presents an interesting review of urology for the year 1910-1911.—Bull. sc. pharmacol. 1911, v. 18, pp. 546-561, 589-611. Best discusses the study of urinary sediments.-Apoth.-Ztg. 1911, v. 26, pp. 844-846, 853-854.

Pearson, William A., points out that urine analysis to-day means more than it did even five years ago and will be of still greater diagnostic value five years from now.-Hahnemann. Month. 1911, v. 46, p. 571.

An unsigned article calls attention to a number of the newer tests used in the analysis of urine.-Ztschr. allg. österr. Apoth.-Ver. 1911, v. 49, pp. 538-539.

Geraghty and Rowntree discuss the phenolsulphonephthalein test for estimating renal function, which they think of immense value from a diagnostic and prognostic standpoint.-J. Am. M. Assoc. 1911, v. 811-816.

Austin and Eisenbrey conclude that the phenolsulphonephthalein test seems to be a better indicator of the ability of the kidney to eliminate the toxic substance responsible for the symptoms of renal insufficiency than are either the anatomic changes or the elimination of total nitrogen or of chlorides.-J. Exper. M. 1911, v. 14, pp. 366–376. See also pp. 462-475.

Wolter discusses the testing of urine with Bellosti's reagent.Pharm. Ztg. 1911, v. 56, p. 232.

"A. C. K." proposes a test by which the presence of methylene blue in the urine may be recognized.-Pract. Drug. 1911, v. 29, Apr., p. 43. Fuhs and Lintz contribute a note on the diagnostic significance of the urinary methylene blue reaction with special reference to malignancy. J. Am. M. Assoc. 1911, v. 56, p. 1882.

Verbrycke, J. Russell, reports observations on the methylene blue test in urine of cancer patients.—Med. Rec. 1911, v. 80, p. 876. Siegfried and Zimmermann discuss the separate estimation of phenol and p-cresol.-Biochem. Ztschr. 1911, v. 34, pp. 462-472. Warbrick, John C., discusses the significance of the chlorides, phosphates, and sulphates of the urine in the last stage of pulmonary tuberculosis. Med. Rec. 1911, v. 79, p. 867.

McCrudden, Francis H., in a paper on the determination of calcium in urine, discusses calcium in the presence of magnesium and phosphates. J. Biol. Chem. 1911, v. 10, pp. 187-199.

Sarvonat and Didier contribute a note on the reaction of the ash of urine. Compt. rend. Soc. Biol. 1911, v. 71, p. 631.

Gérard, Er., presents a note on the presence of traces of chloesterin in normal urine.-Ibid. v. 70, p. 998.

Patein, G., contributes a paper on cystin and cystinuria.—J. Pharm. et Chim., 1911, v. 4, pp. 397-408.

Taylor, Alonzo Englebert, comments on the sources of error in the Folin method for the estimation of creatinine. J. Biol. Chem. 1911, v. 9, pp. 19-20.

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Mendel and Rose report observations on the rôle of the carbohydrates in creatine-creatinine metabolism.-Ibid. v. 10, pp. 213–270.

Walpole, G. Stanley, discusses the direct determination of creatine in pathological urine, by the pink color given in alkaline solution by creatine, but not by creatinine, when a trace of diacetyl is added— J. Physiol. Lond. 1911, v. 42, pp. 301–308.

Mellanby, Edward, presents a short chemical study of a case of cyclic vomiting, with some remarks on creatinuria and acidosis.Lancet, 1911, v. 181, pp. 8-12.

McOscar, J., contributes a brief note on the presence of kiestin in urine during pregnancy.-Brit. M. J. 1911, v. 2, p. 620.

Goodman, Edward H., reports clinical studies in the pepsin and diastase content of urine, and unequivocally disclaims all value for the determination of the ferments in urine per se.-N. York M. J. 1911, v. 93, pp. 777-781.

Pribram and Löwy discuss the occurrence of a lipolytic ferment in urine.-Ztschr. physiol. Chem. 1911-12, v. 76, pp. 489–495.

Kakiuchi, Samuro, presents a contribution on the estimation of fats in pathological urine.-Biochem. Ztschr. 1911, v. 32, pp. 137–144. Lichtwitz, L., reports a study of the colloids in urine.-Ztschr. physiol. Chem. 1911, v. 72, pp. 215-225.

Bernier proposes a method for the determination of glycuronic acid in urine.-Répert. pharm. 1911, v. 23, p. 52.

Higgins and Benedict emphasize the value of the study of carbonnitrogen and calorie-nitrogen ratios; give a method for determining the heat of combustion and carbon of the urine; and point out the advantage of the development of either a volumetric or a wet process, by which determination of carbon in urine can be simply, quickly, and accurately made. Am. J. Physiol. 1911, v. 28, pp. 291–300.

Ducco, C., outlines a rapid method for the detection and estimation of nitrites in urine.-Répert. pharm. 1911, v. 23, p. 78.

Caron, H., discusses the analysis of nitrates in the urine.-Répert. pharm. 1911, v. 23, pp. 385-389.

Schröter, F., discusses the quantitative estimation of hexamethylentetramine in urine.-Arch. exper. Path. u. Pharmakol. 1910-11, v. 64, pp. 161-166.

Green, H. H., presents a note on the detection of potassium in urine, by precipitation as the double cobalti-nitrite of sodium and potassium.-Biochem. J. 1911, v. 6, pp. 69-75.