Robbins Pathologic Basis of DiseasePresenting the latest edition of this popular, comprehensive and practical text of pathology. Written with great clarity for easy readability, this reference offers detailed discussions of genetic disorders, cellular injury and death, neoplasia, the skeletal system and soft tissue tumors, and much more. Completely revised and updated, this edition is even more user-friendly with the use of text boxes for key topics in each chapter and a new full-color design. Features 1200 excellent 4-color illustrations! |
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Page 100
... matrix and the cell- binding domain containing an arginine - glycine - aspartic acid ( RGD ) sequence . The cross - shaped laminin ( B ) molecule spans basement membranes and has extracellular matrix ( ECM ) - and cell - binding domains ...
... matrix and the cell- binding domain containing an arginine - glycine - aspartic acid ( RGD ) sequence . The cross - shaped laminin ( B ) molecule spans basement membranes and has extracellular matrix ( ECM ) - and cell - binding domains ...
Page 303
... matrix is an active pro- cess that can be resolved into several steps : 1. Detachment ( " loosening up " ) of the tumor cells from each other 2. Attachment to matrix components 3. Degradation of extracellular matrix 4. Migration of ...
... matrix is an active pro- cess that can be resolved into several steps : 1. Detachment ( " loosening up " ) of the tumor cells from each other 2. Attachment to matrix components 3. Degradation of extracellular matrix 4. Migration of ...
Page 304
... matrix proteolysis . Migration seems to be medi- ated by two categories of molecules : ( 1 ) tumor cell - de- rived motility factors , and ( 2 ) cleavage products of matrix components ( e.g. , collagen , laminin ) . In the first group ...
... matrix proteolysis . Migration seems to be medi- ated by two categories of molecules : ( 1 ) tumor cell - de- rived motility factors , and ( 2 ) cleavage products of matrix components ( e.g. , collagen , laminin ) . In the first group ...
Contents
GENERAL PATHOLOGY | 1 |
6 | 26 |
Acute and Chronic Inflammation | 50 |
Copyright | |
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Common terms and phrases
abnormal acid activation acute adhesion amyloidosis angiogenesis antibodies antigens apoptosis associated bacteria bind blood cancer carcinogens carcinoma cause CD4+ cell cycle cell death cellular Chapter chemical chromosome chronic clinical collagen colon common cyclin cytokines damage deficiency develop disease disorders drugs edema effects endothelial cells endothelium enzymes epithelial cells extracellular matrix fever fibrosis Figure function gene genetic granulomas growth factor hepatitis host cells human immune increased induce infection infiltrate inflammation inflammatory integrins intracellular involved kinase lesions leukocytes liver lung lymph nodes lymphocytes lymphoma lysosomal macrophages malignant matrix mechanisms mediators membrane metabolism molecular molecules MORPHOLOGY muscle mutations necrosis neoplasms nervous system neutrophils normal occur oncogenes organisms oxidative parasites pathogenesis pathogens pathway patients peptide phagocytosis plasma platelet produce proliferation protein reactions receptor release renal respiratory response result signals skin surface syndrome synthesis T-cell tion tissue toxic toxin tumor tumor cells vascular viral virus viruses vitamin