Essentials of Medicinal Chemistry
This text/reference presents fundamental aspects of medicinal chemistry and contains comprehensive information on approximately 5,000 drugs currently in use, describing their therapeutic uses, their mechanisms of action, and their main side and harmful effects. Employs the latest World Health Organization (WHO) pharmacological classification and provides extensive information for drugs on WHO's latest list of basic or essential pharmaceuticals, including history: chemical, trade and generic names; chemical structure; obtention; physical and chemical properties; mechanisms of action; therapeutic uses; adverse reactions; biotransformation; chemical and pharmacological incompatibilities; bioavailability; dosage; storage; and assay.
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VITAMINS AND HORMONES
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acetylcholine acid activity administration adrenergic adverse reactions agonists airtight alkaloids alkylating amino ampoule analgetics analogs anesthetics Annu antagonists anthelmintic antibacterial antibiotics anticholinergic Assay bacteria benzodiazepines Bioavailability Biochem biological biosynthesis Biotransformation blocking agents blood bromide calcium caused cell cephalosporins Chem Chemical Name chemotherapeutic chloride chloroform Clin Clinical compounds crystalline powder derivatives disease dopamine Dosage dose Drug Res effects enzyme epinephrine erythromycin ester ether example excreted Figure gastrointestinal tract half-life histamine hormones hydrochloride inhibition inhibitors injection interaction intravenous isoniazid isosteres lactam levodopa mechanism of action membrane metabolism metabolites moiety molecular molecule odorless oral route patients penicillins perchloric acid Pharm pharmaceutical Pharmacokinet Pharmacol pharmacological plasma practically insoluble prodrugs produce Prog properties Proprietary Names protein quinidine receptor salts slightly soluble sodium soluble in alcohol soluble in water solution structure substances sulfate sulfonamides Synthesis tablet tetracycline therapeutic therapy titration with 0.1 toxic treatment urine vasodilators York