Bioimaging in Neurodegeneration

Front Cover
Patricia A. Broderick, David N. Rahni, Edwin H. Kolodny
Springer Science & Business Media, Nov 5, 2007 - Medical - 314 pages
Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK « However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Nanoand Microimaging Surgical Anesthesia in Epilepsy Patients
xii
PARKINSONS DISEASE
2
Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy in Parkinsons Disease Structural vs Functional Changes
3
Positron Emission Tomography and SinglePhoton Emission Tomography in the Diagnosis of Parkinsons Disease Differential Diagnosis From Parkins...
13
Positron Emission Tomography in Parkinsons Disease Cerebral Activation Studies and Neurochemical and Receptor Research
25
╣▓│IAltropane SPECT 4 How It Compares to Other Positron Emission Tomography and SinglePhoton Emission Tomography Dopamine Transporters i...
37
Positron Emission Tomography and Embryonic Dopamine Cell Transplantation in Parkinsons Disease
45
ALZHEIMERS DISEASE
58
Pediatric Cortical Dysplasia Positron Emission Tomography Studies
131
Bioimaging LTryptophan in Human Hippocampus and Neocortex Subtyping Temporal Lobe Epilepsy
141
In Vivo Intrinsic Optical Signal Imaging of Neocortical Epilepsy
149
Intraoperative Magnetic Resonance Imaging in the Surgical Treatment of Epilepsy
177
Periodic Epileptiform Discharges Associated With Increased Cerebral Blood Flow Role of SinglePhoton Emission Tomography Imaging
193
Imaging White Matter Signals in Epilepsy Patients A Unique Sensor Technology
199
LEUKODYSTROPHY WHITE MATTER DISEASES
207
Overview of the Leukoencephalopathies An MRI Point of View
209

Neurotoxicity of the Alzheimers βAmyloid Peptide Spectroscopic and Microscopic Studies
59
Functional Imaging and Psychopathological Consequences of Inflammation in Alzheimers Dementia
75
Neurotoxic Oxidative Metabolite of Serotonin 8 Possible Role in Alzheimers Disease
85
Predicting Progression of Alzheimers Disease With Magnetic Resonance
95
Stages of Brain Functional Failure in Alzheimers Disease In Vivo Positron Emission Tomography and Postmortem Studies Suggest Potential Initial Re...
107
EPILEPSY
121
Neocortical Epilepsy αMethylLTryptophan and Positron Emission Tomography Studies
123
Pyramidal Tract Involvement in Adult Krabbes Disease Magnetic Resonance Imaging and Proton Magnetic Resonance Spectroscopy Abnormalities
215
Imaging Leukodystrophies Focus on Lysosomal Peroxisomal and NonOrganelle Pathology
225
Advanced Magnetic Resonance Imaging in Leukodystrophies
239
Childhood Mitochondrial Disorders and Other Inborn Errors of Metabolism Presenting With White Matter Disease
261
Mitochondrial Disease Brain Oxidative Metabolism Studied by │╣P │H and ╣│C Magnetic Resonance Spectroscopy Functional Magnetic Resonance Ima...
297
Index
309
Copyright

Other editions - View all

Common terms and phrases

Bibliographic information