Bioimaging in NeurodegenerationPatricia A. Broderick, David N. Rahni, Edwin H. Kolodny Bioimaging is in the forefront of medicine for the diagnosis and helps to predict the progression of AD via mild cognitive treatment of neurodegenerative disease. Conventional magnetic impairment (MCI) studies. resonance imaging (MRI) uses interactive external magnetic fields Novel neuroimaging technologies, such as neuromolecular and resonant frequencies of protons from water molecules. imaging (NMI) with a series of newly developed BRODERICK ® However, newer sequences, such as magnetization-prepared rapid PROBE sensors, directly image neurotransmitters, precursors, acquisition gradient echo (MPRAGE), are able to seek higher and metabolites in vivo, in real time and within seconds, at separate levels of anatomic resolution by allowing more rapid temporal and selective waveform potentials. NMI, which uses an imaging. Magnetic resonance spectroscopy (MRS) images electrochemical basis for detection, enables the differentiation of metabolic changes, enabling underlying pathophysiologic neurodegenerative diseases in patients who present with mesial dysfunction in neurodegeneration to be deciphered. Neuro- versus neocortical temporal lobe epilepsy. In fact, NMI has some 1 chemicals visible with proton H MRS include N-acetyl aspartate remarkable similarities to MRI insofar as there is technological (NAA), creatine/phosphocreatine (Cr), and choline (Cho); NAA dependence on electron and proton transfer, respectively, and is considered to act as an in vivo marker for neuronal loss and/or further dependence is seen in both NMI and MRI on tissue neuronal dysfunction. By extending imaging to the study of composition such as lipids. |
What people are saying - Write a review
We haven't found any reviews in the usual places.
Contents
xii | |
2 | |
3 | |
13 | |
Positron Emission Tomography in Parkinsons Disease Cerebral Activation Studies and Neurochemical and Receptor Research | 25 |
¹²³IAltropane SPECT 4 How It Compares to Other Positron Emission Tomography and SinglePhoton Emission Tomography Dopamine Transporters i... | 37 |
Positron Emission Tomography and Embryonic Dopamine Cell Transplantation in Parkinsons Disease | 45 |
ALZHEIMERS DISEASE | 58 |
Pediatric Cortical Dysplasia Positron Emission Tomography Studies | 131 |
Bioimaging LTryptophan in Human Hippocampus and Neocortex Subtyping Temporal Lobe Epilepsy | 141 |
In Vivo Intrinsic Optical Signal Imaging of Neocortical Epilepsy | 149 |
Intraoperative Magnetic Resonance Imaging in the Surgical Treatment of Epilepsy | 177 |
Periodic Epileptiform Discharges Associated With Increased Cerebral Blood Flow Role of SinglePhoton Emission Tomography Imaging | 193 |
Imaging White Matter Signals in Epilepsy Patients A Unique Sensor Technology | 199 |
LEUKODYSTROPHY WHITE MATTER DISEASES | 207 |
Overview of the Leukoencephalopathies An MRI Point of View | 209 |
Neurotoxicity of the Alzheimers βAmyloid Peptide Spectroscopic and Microscopic Studies | 59 |
Functional Imaging and Psychopathological Consequences of Inflammation in Alzheimers Dementia | 75 |
Neurotoxic Oxidative Metabolite of Serotonin 8 Possible Role in Alzheimers Disease | 85 |
Predicting Progression of Alzheimers Disease With Magnetic Resonance | 95 |
Stages of Brain Functional Failure in Alzheimers Disease In Vivo Positron Emission Tomography and Postmortem Studies Suggest Potential Initial Re... | 107 |
EPILEPSY | 121 |
Neocortical Epilepsy αMethylLTryptophan and Positron Emission Tomography Studies | 123 |
Pyramidal Tract Involvement in Adult Krabbes Disease Magnetic Resonance Imaging and Proton Magnetic Resonance Spectroscopy Abnormalities | 215 |
Imaging Leukodystrophies Focus on Lysosomal Peroxisomal and NonOrganelle Pathology | 225 |
Advanced Magnetic Resonance Imaging in Leukodystrophies | 239 |
Childhood Mitochondrial Disorders and Other Inborn Errors of Metabolism Presenting With White Matter Disease | 261 |
Mitochondrial Disease Brain Oxidative Metabolism Studied by ³¹P ³H and ¹³C Magnetic Resonance Spectroscopy Functional Magnetic Resonance Ima... | 297 |
309 | |
Other editions - View all
Bioimaging in Neurodegeneration Patricia A. Broderick,David N. Rahni,Edwin H. Kolodny No preview available - 2014 |
Bioimaging in Neurodegeneration Patricia A. Broderick,David N. Rahni,Edwin H. Kolodny No preview available - 2005 |
Bioimaging in Neurodegeneration Patricia A. Broderick,David N. Rahni,Edwin H. Kolodny No preview available - 2007 |
Common terms and phrases
abnormalities acid activity adrenoleukodystrophy Alzheimer Alzheimer’s disease amyloid Ann Neurol areas atrophy basal ganglia binding biochemical blood flow brain Broderick cell cerebral changes choline clinical cognitive correlation cortex cortical dysplasia decreased deficiency dementia demonstrated demyelination detection diagnosis diffuse disorders dopamine transporter dopaminergic enzyme epileptic epileptogenic evaluation FDG PET FDOPA uptake fibrillization focal frontal function gene genetic glucose gray matter hippocampal human ictal increased interictal intraoperative involvement L-Trp lactate lesions leukodystrophy magnetic resonance imaging magnetic resonance spectroscopy metabolism metabolites mitochondrial motor multiple system atrophy mutations myelin neocortex neocortical Neurodegeneration neuroimaging Neurology neurons Neurosci neurotoxicity normal Nucl onset optical oxidation Parkinson’s disease pathology PD patients peptide PET study plaques positron emission tomography progression protein proton putamen receptor regions reported resection scan seizures serotonin signal SPECT striatal striatum surgery syndrome T2-weighted temporal lobe epilepsy tion tissue tracer transplantation visual vitro vivo white matter