Snake Oil Science: The Truth about Complementary and Alternative Medicine

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Oxford University Press, Jul 31, 2009 - Medical - 352 pages
Millions of people worldwide swear by such therapies as acupuncture, herbal cures, and homeopathic remedies. Indeed, complementary and alternative medicine is embraced by a broad spectrum of society, from ordinary people, to scientists and physicians, to celebrities such as Prince Charles and Oprah Winfrey. In the tradition of Michael Shermers Why People Believe Weird Things and Robert Parks's Voodoo Science, Barker Bausell provides an engaging look at the scientific evidence for complementary and alternative medicine (CAM) and at the logical, psychological, and physiological pitfalls that lead otherwise intelligent people--including researchers, physicians, and therapists--to endorse these cures. The books ultimate goal is to reveal not whether these therapies work--as Bausell explains, most do work, although weakly and temporarily--but whether they work for the reasons their proponents believe. Indeed, as Bausell reveals, it is the placebo effect that accounts for most of the positive results. He explores this remarkable phenomenon--the biological and chemical evidence for the placebo effect, how it works in the body, and why research on any therapy that does not factor in the placebo effect will inevitably produce false results. By contrast, as Bausell shows in an impressive survey of research from high-quality scientific journals and systematic reviews, studies employing credible placebo controls do not indicate positive effects for CAM therapies over and above those attributable to random chance. Here is not only an entertaining critique of the strangely zealous world of CAM belief and practice, but it also a first-rate introduction to how to correctly interpret scientific research of any sort. Readers will come away with a solid understanding of good vs. bad research practice and a healthy skepticism of claims about the latest miracle cure, be it St. John's Wort for depression or acupuncture for chronic pain.
 

Contents

The Rise of Complementary and Alternative Therapies
1
A Brief History of Placebos
23
Natural Impediments to Making Valid Inferences
37
Impediments That Prevent Physicians and Therapists from Making Valid Inferences
59
Impediments That Prevent Poorly Trained Scientists from Making Valid Inferences
69
Why Randomized Placebo Control Groups Are Necessary in CAM Research
83
Judging the Credibility and Plausibility of Scientific Evidence
101
Some Personal Research Involving Acupuncture
113
A Biochemical Explanation for the Placebo Effect
143
What HighQuality Trials Reveal About CAM
167
What HighQuality Systematic Reviews Reveal About CAM
199
How CAM Therapies Are Hypothesized to Work
255
Tying Up a Few Loose Ends
277
NOTES
295
INDEX
317
Copyright

How We Know That the Placebo Effect Exists
127

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About the author (2009)

R. Barker Bausell, Ph.D., a professor at the University of Maryland Baltimore, was Research Director of a National Institutes of Health-funded Complementary and Alternative Medicine Specialized Research Center where he was in charge of conducting and analyzing randomized clinical trials involving acupuncture's effectiveness for pain relief. He has also served as a consultant to Prevention and Discover magazines.

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