Research Projects in Dry Eye Syndrome

Front Cover
Horst Brewitt
Karger Medical and Scientific Publishers, 2010 - Medical - 151 pages
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Dry eye is one of the most common disorders encountered in ophthalmological practice. Its symptoms cause considerable discomfort and substantially reduce the patient's quality of life. As it is a complex and multifactorial condition, research investigating dry eye is a matter of great interest all over the world. In this book, the wide range of current basic and clinical research in dry eye and correlated ocular surface diseases is presented by scientists from Germany, Austria and the USA. These renowned authors provide clear and extensive descriptions of their projects, enabling scientists and clinical ophthalmologists to quickly bring themselves up to date with cutting edge research in this field. This overview of research into the pathogenesis and clinical treatment of dry eye is a must for all ophthalmologists dealing with this syndrome and looking to increase their knowledge base.
 

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Contents

Trefoil Factor Family Peptide 3 at the Ocular Surface A Promising Therapeutic Candidate for Patients with Dry Eye Syndrome?
1
Cationic Amino Acid Transporters and βDefensins in Dry Eye Syndrome
12
Antimicrobial Peptides as a Major Part of the Innate Immune Defense at the Ocular Surface
16
Regulation of the Inflammatory Component in Chronic Dry Eye Disease by the EyeAssociated Lymphoid Tissue EALT
23
Intravital Multidimensional RealTime Imaging of the Conjunctival Immune System
40
Generation of Two and ThreeDimensional Lacrimal Gland Constructs
49
Midterm Results of Cultivated Autologous and Allogeneic Limbal Epithelial Transplantation in Limbal Stem Cell Deficiency
57
Laser Scanning Confocal Microscopy for Conjunctival Epithelium Imaging
71
The ex vivo Eye Irritation Test
93
The Lid Margin Is an Underestimated Structure for Preservation of Ocular Surface Health and Development of Dry Eye Disease
108
Diagnostic Markers of Sjögrens Syndrome
123
Hyperosmolarity of the Tear Film in Dry Eye Syndrome
129
Details of Its Mechanism of Action
139
Author Index
148
Subject Index
149
Copyright

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