Fly Models of Human Diseases
Academic Press, Jan 2, 2017 - Science - 454 pages
Fly Models of Human Diseases provides users with a comprehensive survey on fly models of human diseases in the field of developmental biology. It is ideal for researchers in animal and plant development, and for students and professionals working in a variety of fields related to the topic.
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Academy of Sciences accessory gland activity adult amyotrophic lateral sclerosis autophagy cachexia cancer cause Cell Biology cellular clinical complex cytoplasmic defects degeneration Developmental Developmental Biology disorders Drosophila melanogaster Drosophila model Dystroglycan Dystrophin effects epithelial exosomes factors female flies function galactose galactosemia gene expression genome glucose homeostasis Human Molecular Genetics huntingtin Huntington’s identified immune response impaired infection innate immune insulin interactions intestinal Journal kinase knockdown levels loss LRRK2 mammalian mammals mechanisms metabolism mice microbiota mitochondrial mitochondrial disease motor neurons mouse mtDNA muscle mutations National Academy neurodegenerative Neuroscience nuclear oncogenic overexpression parkin Parkinson’s disease pathogenesis pathogenic patients peptide Perrimon phenotypes PINK1 PLoS polyQ promotes prostate proteasome protein protein aggregates receptor regulation Research RNSCs role screen secondary cells seminal signaling pathways sleep stem cells stem-cell studies target therapeutic tissue toxicity transcription transgenic tumor ubiquitin VAPB variants Wang wild-type Wolfner Zhang