Designing Clinical ResearchDesigning Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly. |
Contents
IV | 3 |
VII | 8 |
VIII | 13 |
IX | 14 |
X | 15 |
XII | 17 |
XIII | 18 |
XIV | 19 |
XCII | 196 |
XCIII | 199 |
XCIV | 200 |
XCV | 202 |
XCVI | 203 |
XCVII | 204 |
XCVIII | 207 |
C | 208 |
XV | 22 |
XVI | 23 |
XVII | 25 |
XIX | 27 |
XX | 28 |
XXI | 29 |
XXII | 32 |
XXIII | 33 |
XXIV | 35 |
XXV | 36 |
XXVI | 37 |
XXVII | 38 |
XXVIII | 39 |
XXIX | 41 |
XXX | 45 |
XXXI | 46 |
XXXII | 47 |
XXXIV | 48 |
XXXV | 49 |
XXXVI | 51 |
XXXVIII | 54 |
XXXIX | 59 |
XL | 62 |
XLI | 63 |
XLII | 65 |
XLIV | 71 |
XLV | 73 |
XLVI | 75 |
XLVII | 76 |
XLVIII | 81 |
XLIX | 82 |
L | 83 |
LI | 84 |
LII | 86 |
LIII | 89 |
LIV | 90 |
LV | 91 |
LVI | 92 |
LVII | 93 |
LVIII | 97 |
LIX | 100 |
LX | 103 |
LXI | 104 |
LXII | 109 |
LXIV | 131 |
LXV | 132 |
LXVI | 137 |
LXVII | 141 |
LXIX | 143 |
LXX | 144 |
LXXI | 145 |
LXXII | 146 |
LXXIII | 147 |
LXXV | 150 |
LXXVI | 152 |
LXXVII | 154 |
LXXVIII | 159 |
LXXIX | 160 |
LXXX | 163 |
LXXXII | 170 |
LXXXIII | 179 |
LXXXIV | 180 |
LXXXV | 181 |
LXXXVI | 183 |
LXXXVII | 186 |
LXXXVIII | 188 |
LXXXIX | 192 |
XC | 193 |
XCI | 194 |
CI | 211 |
CII | 213 |
CIII | 218 |
CIV | 219 |
CV | 220 |
CVI | 223 |
CVII | 225 |
CIX | 226 |
CX | 232 |
CXI | 235 |
CXII | 236 |
CXIII | 237 |
CXV | 241 |
CXVII | 250 |
CXVIII | 252 |
CXIX | 253 |
CXX | 254 |
CXXI | 255 |
CXXII | 257 |
CXXIII | 261 |
CXXIV | 266 |
CXXV | 267 |
CXXVI | 268 |
CXXVIII | 269 |
CXXX | 271 |
CXXXI | 272 |
CXXXII | 276 |
CXXXIII | 278 |
CXXXIV | 285 |
CXXXV | 287 |
CXXXVI | 288 |
CXXXVII | 289 |
CXXXVIII | 291 |
CXXXIX | 293 |
CXL | 294 |
CXLI | 299 |
CXLIII | 301 |
CXLV | 303 |
CXLVI | 309 |
CXLVII | 310 |
CXLVIII | 315 |
CXLIX | 316 |
CL | 317 |
CLI | 318 |
CLIII | 319 |
CLV | 320 |
CLVI | 321 |
CLVIII | 322 |
CLXI | 323 |
CLXIV | 324 |
CLXV | 325 |
CLXVI | 326 |
CLXVII | 329 |
CLXVIII | 330 |
CLXXI | 331 |
CLXXII | 332 |
CLXXIII | 333 |
CLXXIV | 334 |
CLXXVI | 337 |
CLXXVIII | 339 |
CLXXIX | 341 |
CLXXX | 342 |
CLXXXII | 344 |
CLXXXIII | 345 |
CLXXXIV | 347 |
CLXXXV | 348 |
CLXXXVI | 350 |
353 | |
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Common terms and phrases
actually additional advantage allow alternative analysis answer apply approach appropriate assess assigned association bias blinded calculation cancer case-control study cause Chapter clinical trials cohort collection compared confounding consider continuous database determine developing disease drug effect error estimate ethical examination example factor findings follow-up forms funding hypothesis identify important increase individual inferences institution interest interval intervention investigator involved less matched mean measurements methods myocardial infarction observed outcome outcome variable participants patients period person placebo population possible potential practice predictor present problem procedures proportion proposal protocol questionnaire randomized ratio reasonable receive records recruitment reduce relative represent require research question responses risk sample sample size selected smoking sometimes specific standard statistical strategies subjects Table treatment usually validity values variables weight women