Neurobiology of Psychiatric Disorders, Volume 106Thomas E Schlaepfer, Charles B. Nemeroff This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment.
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Contents
Psychiatry and neuroscience history | 1 |
Receptor signaling and the cell biology of synaptictransmission | 9 |
Human genetics of schizophrenia | 37 |
Neurological and psychiatric aspects of emotion | 53 |
Research methods cognitive neuropsychological methods | 75 |
Structural imaging in psychiatric disorders | 89 |
Human functional neuroimaging | 97 |
Neurotransmitters and neuropeptides in depression | 107 |
Substance abuse disorders | 419 |
Cognitive impairment in schizophrenia profile courseand neurobiological determinants | 433 |
Eating disorders anorexia and bulimia nervosa | 447 |
Personality disorders | 463 |
Psychiatric nonmotor aspects of Parkinsons disease | 477 |
Stroke | 491 |
Huntingtons disease | 507 |
Sleep disorders | 527 |
Animal models of psychiatric disorders | 137 |
Psychiatric epidemiology | 167 |
Emerging methods in the molecular biologyof neuropsychiatric disorders | 191 |
Clinical psychoneuroimmunology | 211 |
Psychiatric rating scales | 227 |
Unipolar depression | 239 |
Bipolar disorder | 251 |
The neurobiology and treatment of latelife depression | 265 |
Seasonal affective disorder | 279 |
Biological and clinical framework for posttraumaticstress disorder | 291 |
Generalized anxiety disorder | 343 |
Panic disorder | 363 |
Obsessivecompulsive disorder | 375 |
Attentiondeficithyperactivity disorder | 391 |
Autism and related disorders | 407 |
Depression and cardiovascular disorders | 541 |
Psychiatric disorders among cancer patients | 557 |
Chronic fatigue syndrome | 573 |
Neurocognitive deficits in patients with human immunodeficiency virus infection | 589 |
Gastrointestinal disorders | 607 |
Role of psychotherapy in the management of psychiatric diseases | 633 |
Pharmacology and neuroimaging of antidepressant action | 643 |
Antipsychotic drugs | 657 |
Anxiolytics | 669 |
Brain stimulation therapies for neuropsychiatric disease | 681 |
Chronotherapeutics light and wake therapy as a class of interventions for affective disorders | 697 |
Pharmacogenetics of antidepressants and mood stabilizers | 715 |
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abnormalities activity acute addiction ADHD adolescents adults affective disorder agonist amygdala animal models anosognosia antidepressant anxiety disorder apathy Arch Gen Psychiatry assessment autism behavior Biol Psychiatry bipolar disorder Brain Res cell chronic Clin clinical comorbid controls correlates cortical cortisol criteria decreased deficits dementia diagnosis dopamine double-blind drug DSM-IV dysfunction effects emotional evidence factors frontal functional GABA gene genetic glucocorticoid glutamate Health hippocampus hormone HPA axis human Huntington's disease hyperactivity imaging increased kinase lesions levels major depression medication memory ment mental mood disorders motor nervosa neural Neurobiology neuroimaging neurons Neurosci obsessive-compulsive disorder onset panic disorder Parkinson's disease personality disorder Pharmacol placebo placebo-controlled poststroke posttraumatic stress disorder prefrontal cortex prevalence psychiatric disorders Psychiatry Psychol PTSD rates rats receptor regions reported response risk role schizophrenia seasonal affective disorder serotonin sleep social specific stimulation stroke studies symptoms syndrome therapy tion trauma treatment