Nucleotide Analogues as Antiviral Agents

Front Cover
John C. Martin, American Chemical Society. Division of Carbohydrate Chemistry, American Chemical Society. Division of Medicinal Chemistry
American Chemical Society, 1989 - Language Arts & Disciplines - 190 pages
Largely in response to the AIDS epidemic, the amount of research directed toward the discovery of antiviral agents has greatly expanded. This new volume focuses on the potential of nucleotides to exert potent in vivo antiviral effects. It presents the findings of an international group of scientists who are carrying out research at the forefront of the nucleotide drug design. Twelve chapters describe many new concepts and results, much of which has been previously unpublished. This book assembles a valuable collection of information, offering insight into this increasingly important research topic.

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Contents

Synthesis of Acyclonucleoside Phosphonates for Evaluation
17
Structural Requirements for Enzymatic Activation
35
Phosphonylmethyl Ethers of Nucleosides and Their Acyclic
51
Copyright

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About the author (1989)

John C. Martin is at Bristol-Myers Co..