Rethinking Substance Abuse: What the Science Shows, and What We Should Do about ItWilliam R. Miller, Kathleen M. Carroll While knowledge on substance abuse and addictions is expanding rapidly, clinical practice still lags behind. This book brings together leading experts to describe what treatment and prevention would look like if it were based on the best science available. The volume incorporates developmental, neurobiological, genetic, behavioral, and social–environmental perspectives. Tightly edited chapters summarize current thinking on the nature and causes of alcohol and other drug problems; discuss what works at the individual, family, and societal levels; and offer robust principles for developing more effective treatments and services.
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Contents
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25 | |
What Can Human Brain Imaging Tell Us about | 46 |
Genetics of Substance Use Disorders | 61 |
Developmental Perspectives on the Risk for Developing | 97 |
Comorbid Substance Use Disorders | 115 |
Motivational Factors in Addictive Behaviors | 134 |
Family and Other Close Relationships | 166 |
Social Contexts and Substance Use | 182 |
The Glass Would Be Half | 223 |
Pharmacotherapy of Addictive Disorders | 240 |
Religion Spirituality and the Troublesome Use | 257 |
Creating a Responsive | 275 |
Ten Principles | 293 |
Index | 313 |
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abstinence acamprosate addiction adolescents adults agonists alcohol and drug alcohol dependence Alcoholics Anonymous amygdala approaches associated behavioral therapies brain chapter chronic clients clinical cocaine cognitive comorbid comorbid disorders context differences disulfiram dopamine drinkers drinking drug abuse drug problems drugs of abuse effects ence environmental ethnographic example factors family members function GABA genes genetic groups Hispanic increase individuals influence interaction interventions involvement marijuana medications ment mental health methadone misuse modules motivation motivational interviewing mu opioid receptor naltrexone negative neurotransmitter nicotine norms nucleus accumbens opiate opioid opioid peptides outcomes parents patients patterns peer person pharmacological pharmacotherapy potential prevention problematic psychiatric Psychology receptor recovery reduce relapse response reward risk Robust Principles role self-change smoking social network specific spiritual stance strategies studies substance abuse treatment substance use disorders substance use problems substance users tion treat treatment programs twin studies vulnerability
Popular passages
Page 3 - Do not look at wine when it is red, when it sparkles in the cup and goes down smoothly. At the last it bites like a serpent, and stings like an adder.
Page 17 - It is that the sciences do not try to explain, they hardly even try to interpret, they mainly make models. By a model is meant a mathematical construct which, with the addition of certain verbal interpretations, describes observed phenomena. The justification of such a mathematical construct is solely and precisely that it is expected to work — that is, correctly to describe phenomena from a reasonably wide area.
Page 255 - J. et al. (2004). Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: A randomized placebo-controlled trial. Archives of General Psychiatrv, 61, 264-272.
Page 36 - ... Within-system adaptations have been hypothesized wherein neurochemical changes associated with the same neurotransmitters implicated in the acute reinforcing effects of drugs are altered during the development of dependence.
Page 44 - CRF perikarya include the central nucleus of the amygdala, the bed nucleus of the stria terminalis and the substantia innominata.
Page 8 - spiritualistic" theory of scholasticism and of common-sense. Another and a less obvious way of unifying the chaos is to seek common elements in the divers mental facts rather than a common agent behind them, and to explain them constructively by the various forms of arrangement of these elements, as one explains houses by stones and bricks. The "associationist...
Page 255 - Report prepared for the National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Department of Health and Human Services.
Page 77 - Cadoret, RJ, Yates, WR, Troughton, E., Woodworth, G., & Stewart, MA (1995). Adoption study demonstrating two genetic pathways to drug abuse. Archives of General Psychiatry, 5.2(1), 42-52.
Page 45 - Stewart, J. (2003). The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology 168, 3-20.