Catalog of Teratogenic AgentsThis reference presents entries on more than 3,100 agents that can cause birth defects, including chemicals, drugs, physical factors, gene mutations, and viruses. Approximately 800 of the agents are new to the 11th edition; 150 of these are newly listed agents. The entry on each agent lists human data (when it exists), a brief summary of published |
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abnormalities adverse effects adverse fetal effects agent anomalies Appl associated Birth Defects cleft palate congenital defects decreased developmental toxicity studies effects were found embryos embryotoxicity exencephaly exposure fects fetal weight fetus folic acid found no adverse found no increase gavaged gave rats gene Genetics gestation growth retardation Gynecol Heinonen highest dose hydrocephalus hydrochloride increase in defects infants injected intraperitoneally intravenously kg daily kg on days kg orally kg per day Lancet malformations maternal toxicity mg per kg mice microgm mothers mutation neural tube defects newborns Obstet offspring organogenesis Oyo Yakuri percent Pharmacol postnatal postnatal study preg pregnancy pregnant rats prenatal produced rat embryos rats and rabbits rats on days reduced reported Reproduction studies Reproductive and developmental Reproductive Toxicology resorptions skeletal defects study in rats subcutaneously syndrome teratogenesis teratogenic effects teratogenicity Teratogenicity study Teratological study Teratology tion Toxicol Toxicology treated trimester vitro women Yakuri to Chiryo