Advanced Practical Organic Chemistry, Second EditionThe first edition of this book achieved considerable success due to its ease of use and practical approach, and to the clear writing style of the authors. The preparation of organic compounds is still central to many disciplines, from the most applied to the highly academic and, more tan ever is not limited to chemists. With an emphasis on the most up-to-date techniques commonly used in organic syntheses, this book draws on the extensive experience of the authors and their association with some of the world's mleading laboratories of synthetic organic chemistry. In this new edition, all the figures have been re-drawn to bring them up to the highest possible standard, and the text has been revised to bring it up to date. Written primarily for postgraduate, advanced undergraduate and industrial organic chemists, particularly those involved in pharmaceutical, agrochemical and other areas of fine chemical research, the book is also a source of reference for biochemists, biologists, genetic engineers, material scientists and polymer researchers. |
Contents
Safety | 3 |
3 | 13 |
4 | 20 |
Equipping the laboratory and the bench | 36 |
10 | 49 |
Introduction | 65 |
5 | 98 |
Gases | 107 |
4 | 159 |
55 | 168 |
Working up the reaction | 178 |
Purification | 184 |
Small scale reactions | 227 |
Large scale reactions | 236 |
Characterization | 250 |
Trouble shooting | 258 |
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Common terms and phrases
3-way tap 4A sieves acetate acid alcohol allow apparatus aqueous argon bath bottle bubbler burette butyllithium Calcium hydride cannula Carbon carefully carried Chapter chemical chloride chromatography cm³ column compounds condenser connected containing cooling crystals cylinder database diazomethane dichloromethane diethyl ether distillation double manifold dried drying agent elution ethanol evaporate Figure filter fitted flash chromatography fractions funnel gases glass glassware Grignard reagents heating high vacuum hplc hydrogen Index inert atmosphere inert gas inert gas system liquid lithium Luer metal method moisture molecular sieves monitoring mplc nitrogen organic chemistry Organic Synthesis Pasteur pipette polar prepared pressure procedure purification reaction flask reaction mixture reaction vessel reagents remove round-bottom flask running sample sealed Section separation septum set-up shown in Fig silica simple small scale sodium solid solution solvent spectra stirrer stirring syringe syringe needle techniques Teflon temperature tlc plate tube usually valve vent volume
References to this book
Catalysts for Fine Chemical Synthesis, Hydrolysis, Oxidation and Reduction Stanley M. Roberts,Geraldine Poignant No preview available - 2002 |